Results 41 to 50 of about 7,525 (279)
Konstruktivisme, konstruksionisme en maatskaplike werk
Koers : Bulletin for Christian Scholarship, 2000 Constructivism, constructionism and social work In this article the constructivistic framework of reasoning is illustrated with reference to the premises of the structure determinism of Maturana, Kelly's personality constructs theory, and the radical ...
M.J.M. du Plessis, S.B. Ferreira
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Social Constructionism in the Context of Organization Development
SAGE Open, 2013 The world faces rapid changes that call for new epistemologies and methodologies that can generate innovative forms of “being” and “doing” within organizations.
Celiane Camargo-Borges +1 more
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SocietàMutamentoPolitica: Rivista Italiana di Sociologia, 2018 Note critiche attraverso i testi di Donileen R. Loseke e Joel Best (a cura di), special issues on Constructionist Futures: New Directions in Social Problems Theory, in «Qualitative Sociology Review», vol. XI, n.
Enrico Caniglia
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
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Understanding Ulcers: Medical Knowledge, Social Constructionism, and Helicobacter Pylori [PDF]
, 1996 The study of historical change in the content of medical knowledge in regard to specific illnesses or diseases provides sociologists with the opportunity to investigate both social processes and social theory.
Collyer, Fran, Fran Collyer
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
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