Results 91 to 100 of about 7,666,118 (290)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Portaria Nº. 3.060 de 28 de novembro de 2007

open access: yesRevista Gestão & Saúde, 2010
Regulates the application of financial incentive for implementation of Component for Qualification of NHS management block financing for Management SUS with regard to regulation, control, evaluation,auditing and monitoring, popular participation and ...
Ministério da Saúde
doaj  

DECONSTRUCTION OF IDEOLOGICAL HEGEMONY OF LANGUAGE-CULTURE MAINTENANCE IN SUNDANESE MEDIA [PDF]

open access: yes, 2012
The media, a controlling discourse, is presupposed to perform social power of groups that have ability to control the minds of other groups. The practice of this mind control involves more than acquiring beliefs.
Sari , Retno Purwani
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Visioni dell’educazione: il caso di un penitenziario femminile nell’entroterra paulista

open access: yesDiacronie. Studi di Storia Contemporanea, 2013
The article analyzes the educational process expressed in letters from women inmates and former inmates who participated between 2004 and 2007, of social reintegration program in a women’s prison in Ribeirao Preto, in Sao Paulo state. As the letters were
Wlaumir Donisete de Souza (wlaumir@hotmail.com) si è laureato in Filosofia presso la PUC (Ponteficia Università Cattolica del Rio Grande do Sul) e in Storia presso la Faculdade de História, Direito e Serviço Social dell’Universidade Estadual Paulista Júlio de Mesquita Filho. Si è addottorato in Sociologia presso la Faculdade de Ciências e Letras della stessa università ed è professore nel Centro Universitário Barão de Mauá, a Ribeirão Preto nello Stato di São Paulo.   +1 more
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The Theory of Social Control and the Social Psychology of Dissatisfaction: Inhibition, regression and isolation in a cultural context

open access: yesGrounded Theory Review: An International Journal, 2011
The Theory of Social Control (TSC) is grounded in satisfaction and happiness research. The study investigated the reasons behind relatively low levels of civil and personal satisfaction, subjective social well-being and experienced happiness in the post ...
Orsolya Selymes, PhD Candidate
doaj  

Controle Social

open access: yesRevista Simetria do Tribunal de Contas do Município de São Paulo, 2016
O presente estudo apresenta uma reflexão sobre o controle social, tendo como marco histórico a década de 1990, período das primeiras regulamentações da Constituição Federal de 1988. A escolha do tema deriva do fato de que a participação social de forma institucionalizada, objeto de estudos por parte de diversos pesquisadores, desperta interesse não ...
openaire   +1 more source

A measurement of crime control-based social exclusion [PDF]

open access: yes, 2016
Comparative criminal justice policy has a strong inclination to confront national crime control systems in accordance to corresponding levels of punitiveness.
García-España, Elisa
core  

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