Results 91 to 100 of about 7,059,412 (353)

Le gouvernement sécuritaire palestinien au prisme de l’émeute

open access: yesRevue des Mondes Musulmans et de la Méditerranée, 2020
Since 2007, the role of the security apparatus in the Palestinian Authority's (PA) management of populations under its control has increased significantly.
Minas Ouchaklian
doaj   +1 more source

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1006-1028, April 2025.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Mental illness in prisons: true diagnosis or social control? [PDF]

open access: yes, 2013
The poster (presented at the Annual Scientific Meeting of the Mental Health Research Network 2013) questions the validity of certain mental health diagnoses within forensic ...
Harper, Craig
core  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

WARP: A ICN architecture for social data

open access: yes, 2013
Social network companies maintain complete visibility and ownership of the data they store. However users should be able to maintain full control over their content.
Angius, Fabio   +3 more
core   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, Volume 599, Issue 9, Page 1222-1235, May 2025.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

The Theory of Social Control and the Social Psychology of Dissatisfaction: Inhibition, regression and isolation in a cultural context

open access: yesGrounded Theory Review: An International Journal, 2011
The Theory of Social Control (TSC) is grounded in satisfaction and happiness research. The study investigated the reasons behind relatively low levels of civil and personal satisfaction, subjective social well-being and experienced happiness in the post ...
Orsolya Selymes, PhD Candidate
doaj  

Socialization resources in children and adolescents from Russian speaking migrants in Germany [PDF]

open access: yesПсихологическая наука и образование (2007. Online), 2013
We discuss the problems of Russian-speaking families with children who live in Germany, on the language of communication and identification based on nationality, self-esteem of children and assessment of their qualities by parents, the key events before ...
R.V. Chirkina, S.E. Aruin
doaj  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

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