Results 91 to 100 of about 28,362,069 (364)

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Portaria Nº. 3.060 de 28 de novembro de 2007

open access: yesRevista Gestão & Saúde, 2010
Regulates the application of financial incentive for implementation of Component for Qualification of NHS management block financing for Management SUS with regard to regulation, control, evaluation,auditing and monitoring, popular participation and ...
Ministério da Saúde
doaj  

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Introduction: Qualitative Research in Criminology

open access: yesForum: Qualitative Social Research, 2002
This paper begins with a brief overview of research traditions that paved the way for qualitative methods in criminological research (labeling approach and critical criminology). In addition, it outlines recent trends in qualitative criminology.
Michael Meuser, Gabi Löschper
doaj  

Evaluating the Effectiveness of a Goal-Directed Intervention on the Social Interaction of Children with Neurodevelopmental Disabilities [PDF]

open access: yes, 2012
This study sought to address social interaction needs of children with neurodevelopmental disabilities through an eight week intervention focusing on social skills at Spaulding Youth Center (SYC), a residential facility in Northeast United States.
Gatlin, Natalie
core   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Crime and Social Control in Terms of Globalization

open access: yesПроблеми на постмодерността, 2017
Many studies show that regardless of local characteristic in terms of globalization criminal networks are transnational, and local and regional crime are under control of organized crime.
Valentina Zlatanova
doaj  

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Digital Exhibitionism The Age of Exposure

open access: yesCulture Unbound: Journal of Current Cultural Research, 2010
Web 2.0 has expanded the possibilities of digital creative production by individu-als and enabled the digitalisation of private life experiences. This study analyses how social media contributes to the making of personal biographies and discusses the ...
Ana María Munar
doaj   +1 more source

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