Results 111 to 120 of about 7,469,552 (341)

Bureau-repression: Administrative Sanction and Social Control in Modern Spain

Oñati Socio-Legal Series, 2015
This paper explains the creation of an intelligible suggestion for better understanding the administrative sanction in many disciplines in social sciences: the bureau-repression.
Pedro Oliver Olmo, Jesús-Carlos Urda Lozano   +1 more
doaj  

Defending Others Online: The Influence of Observing Formal and Informal Social Control on One's Willingness to Defend Cyberhate Victims. [PDF]

Int J Environ Res Public Health, 2023
Costello M, Hawdon J, Reichelmann AV, Oksanen A, Blaya C, Llorent VJ, Räsänen P, Zych I.   +7 more
europepmc   +1 more source

Continuous Additive Peer Review: A New System to Control Social Loafing in Group Projects [PDF]

, 2010
Amit Poddar
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Disrupted computations of social control in individuals with obsessive-compulsive and misophonia symptoms. [PDF]

iScience, 2022
Banker SM, Na S, Beltrán J, Koenigsberg HW, Foss-Feig JH, Gu X, Schiller D.   +6 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Crime and Social Control in Terms of Globalization

Проблеми на постмодерността, 2017
Many studies show that regardless of local characteristic in terms of globalization criminal networks are transnational, and local and regional crime are under control of organized crime.
Valentina Zlatanova
doaj  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Conhecimento dos usuários, trabalhadores da saúde e gestores sobre conselheiros e Conselhos de Saúde

Saúde em Debate
A criação de um espaço democrático de participação na condução do Sistema Único de Saúde (SUS) constituiu indubitável conquista dos brasileiros. O pleno exercício deste direito implica, no entanto, no conhecimento do próprio direito, dos espaços e dos ...
Camila Sartori Martins, Michele Thaís Sartori, Helena Luiza Douat Dietrich, Fabiane Barbero Klem, Camilo Dallagnol, Guilherme Souza Cavalcanti de Albuquerque, Paulo de Oliveira Perna, Samya Mehanna   +7 more
doaj