Results 21 to 30 of about 11,754,435 (295)

The association of social frailty with intrinsic capacity in community-dwelling older adults: a prospective cohort study

BMC Geriatrics, 2021
Background Social frailty is associated with poor health outcomes; however, its effects on healthy aging indicators have not been adequately investigated.
Chi Hsien Huang, Kiwako Okada, Eiji Matsushita, Chiharu Uno, Shosuke Satake, Beatriz Arakawa Martins, Masafumi Kuzuya   +6 more
doaj   +1 more source

A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts [PDF]

, 2020
Phenotype-specific omic expression patterns in people with frailty could provide invaluable insight into the underlying multi-systemic pathological processes and targets for intervention.
Zürbig, Petra, Viña, J., Zürbig, P., Lippi, G., García-Palmero, Irene, Lippi, Giuseppe, Martínez, J. G., Erusalimsky, Jorge D., Carrie, I., Carnicero, José, Sinclair, Alan J., Carnicero, J., Hardman, Timothy C., García-Palmero, I., Walter, Stefan, Abugessaisa, Imad, FEART-COURET, Catherine, Peres, Karine, Weber, Daniela, Grune, T., Peres, K., Mischak, H., Jansen-Dürr, P., Sinclair, Alan J, Walter, S., Helmer, C., Rodriguez-Mañas, L., Feart, C., Grune, Tilman, Tegner, J., Colpo, M., Miñambres-Herraiz, R., Viña, José, Fiorillo, Edoardo, Colpo, Marco, Mischak, Harald, Cesari, Matteo, Martínez, Jorge García, Butcher, Lee, Garcia-Garcia, F.J., Fiorillo, E., Cucca, Francesco, Garcia-Garcia, Francisco Jose, Hardman, Timothy C, Grillari, J., Tegner, Jesper, Weber, D., Feart, Catherine, Abugessaisa, I., Hardman, T.C., Olaso, G., on behalf of the FRAILOMIC initiative, Dartigues, J-F, Sinclair, A. J., Grillari, Johannes, Bandinelli, Stefania, Miñambres-Herraiz, Rebeca, Helmer, Catherine, Rodriguez-Mañas, Leocadio, Erusalimsky, Jorge, Bandinelli, S., Gomez-Cabrero, David, Bonaguri, C., Jansen-Dürr, Pidder, Palomares, L.B., Olaso, Gloria, Palomares, Lucia Bernad, Erusalimsky, Jorge D, Bonaguri, Chiara, Hackl, Matthias, Hackl, M., Carrie, Isabelle, Cesari, M., Cucca, F., Dartigues, Jean-François   +74 more
core   +1 more source

Associations of social isolation, social participation, and loneliness with frailty in older adults in Singapore: a panel data analysis

BMC Geriatrics, 2022
Background There is a shortage of research evidence about how social isolation, social participation, and loneliness were longitudinally associated with frailty. This study was to 1) examine the associations of social isolation, social participation, and
Lixia Ge, Chun Wei Yap, Bee Hoon Heng
doaj   +1 more source

Cardiovascular risk profile and frailty in a population-based study of older British men. [PDF]

, 2015
Frailty in older age is known to be associated with cardiovascular disease (CVD) risk. However, the extent to which frailty is associated with the CVD risk profile has been little studied.
Papacosta, AO, Arianayagam, DS, Whincup, PH, Ramsay, SE, Iliffe, S, Lennon, LT, Cryer, J, Wannamethee, SG   +7 more
core   +1 more source

P35 Psychological frailty and social frailty in older adults: a scoping review [PDF]

SSM Annual Scientific Meeting, 2021
Background Frailty is increasingly being considered as multidimensional and can encompass physical, cognitive, psychological, and social frailty domains. However, while the physical and cognitive domains of frailty are established within the evidence base, there remains a lack of consensus over the psychological and social aspects of frailty ...
Mische Mckelvie, Michael Donnelly, Dermot O’Reilly, Sharon Cruise   +3 more
openaire   +1 more source

Inflammatory markers and incident frailty in men and women:the English Longitudinal Study of Ageing [PDF]

, 2013
Cross-sectional studies show that higher blood concentrations of inflammatory markers tend to be more common in frail older people, but longitudinal evidence that these inflammatory markers are risk factors for frailty is sparse and inconsistent.
Gale, Catharine R, Cooper, Cyrus, Baylis, D, Sayer, AA, Cooper, C, Gale, CR, Sayer, Avan Aihie, Baylis, Daniel, Gale, Catharine R.   +8 more
core   +1 more source

Social Frailty Among Community-Dwelling Older Adults: Recommended Assessments and Implications

Annals of Geriatric Medicine and Research, 2018
Even though social factors that determine frailty in older people contribute to adverse health outcomes, there is little consensus in terms of the definition of social frailty.
Hyuma Makizako, Kota Tsutsumimoto, Hiroyuki Shimada, Hidenori Arai   +3 more
doaj   +1 more source

A covariance-based test for shared frailty in multivariate lifetime data [PDF]

, 2012
We decompose the score statistic for testing for shared finite variance frailty in multivariate lifetime data into marginal and covariance-based terms.
Kimber, Alan, Sarker, Shah-Jalal
core   +1 more source

Social Frailty in the COVID-19 Pandemic Era [PDF]

Frontiers in Psychiatry, 2020
Special attention and efforts to protect from or reduce health-related outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus triggering coronavirus disease 2019 (COVID-19), should be applied in susceptible populations, including frail older people.
Madia Lozupone, Maddalena La Montagna, Ilaria Di Gioia, Rodolfo Sardone, Emanuela Resta, Emanuela Resta, Antonio Daniele, Antonio Daniele, Gianluigi Giannelli, Antonello Bellomo, Francesco Panza   +10 more
openaire   +5 more sources

Social Vulnerability and Frailty in Hospitalized Older Adults

Canadian Geriatrics Journal, 2023
Background Social vulnerability is the accumulation of disadvantageous social circumstances resulting in susceptibility to adverse health outcomes. Associated with increased mortality, cognitive decline, and disability, social vulnerability has primarily been studied in large population databases rather than frail hospitalized individuals.
Mah, Jasmine C., Godin, Judith, Stevens, Susan J., Keefe, Janice M., Rockwood, Kenneth, Andrew, Melissa K.   +5 more
openaire   +2 more sources