Results 101 to 110 of about 3,093,745 (311)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Understanding socio-economic inequalities in childhood respiratory health [PDF]
Asthma is the most common chronic disease of childhood. Recent evidence has shown a socio-economic gradient in its distribution. This paper examines whether a number of factors argued to have led to a rise in the incidence of asthma might also explain ...
Carol Propper, John A. Rigg
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
, 2012 Don Dunstan Oral History Project interview transcripts. No conditions are imposed on the reuse of this transcript by the interviewee.Interview with Ian Cox by Bruce Guerin on 5 July 2007.
Cox, Ian [Interviewee] +1 more
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Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
A cost-benefit approach to labor market reform [PDF]
Labor reforms in Latin America have been scarce compared with the pace of structural reforms aimed at liberalizing product and capital markets. Some analysts contend that without continued liberalization labor market performance will fail to improve ...
Carmen Pages
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Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
The evolution of water culture in Malta : an analysis of the changing perceptions towards water throughout the ages [PDF]
, 2008 Since time immemorial, the provision of water in sufficient quantities has been one of the most pressing national problems. This paper will try to analyze the changing public perceptions towards water and its use throughout the last two millennia ...
Attard, George +3 more
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
THE MAIN TENDENCIES OF PUBLIC MANAGEMENT REFORMS– FROM A HUNGARIAN POINT OF VIEW [PDF]
Over the course of human history each state decided on its own how broadly and how extensively to encroach on social conditions, i.e. which tasks to take on. However, the growth of state tasks and abstractions by the state (taxation) is a historical fact,
András TORMA
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