Results 121 to 130 of about 2,906,069 (317)

The “Constitution in Exile” as a Problem for Legal Theory [PDF]

open access: yes, 2014
How does one defend a constitutional theory that’s out of the mainstream? Critics of originalism, for example, have described it as a nefarious “Constitution in Exile,” a plot to impose abandoned rules on the unsuspecting public.
Sachs, Stephen E.
core   +2 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Remember the Fillmore: The Lingering History of Urban Renewal in Black San Francisco

open access: yes, 2012
In the summer of 2008, I moved to San Francisco, California. I lived in the city for three months. As a researcher, my objective was to learn more about Mayor Gavin Newsome’s African-American Out-Migration Task Force.
Jackson, Christina, Jones, Nikki
core  

Українська національно-демократична революція 1917-1921 років у регіональних шкільних підручниках з історії (Ukrainian national democratic revolution of 1917-1921 in regional school history textbooks) [PDF]

open access: yes, 2017
Пізнання учнівською молоддю суті української державності розпочинається з бажання пізнавати свій край. Зміст шкільних підручників створює умови для вироблення особистісного ставлення школярів до тих явищ і процесів, які відбувались на території краю ...
Власюк, S. (С. Vlasiuk)
core  

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Dakwah Dalam Konteks Pluralitas Budaya Lokal [PDF]

open access: yes, 2007
Islam is religion which is spread out with da 'wa activities. Without that, it would not be as developed as nowadays. In spreading out Islamic teaching to the mad'u, wisdom is really needed. One way to actualize it is by considering the social conditions
Muridan, M. (Muridan)
core  

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Economic Theories of Foreign Trade Transactions [PDF]

open access: yes
The international experience/practice shows that inside foreign trade relations has sought to lay the ground to uniform rules and to base an orderly development of international trade, so that economic operators engaged in foreign trade can trade with ...
Paliu-Popa, Lucia
core   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy