Results 131 to 140 of about 3,093,745 (311)
Orientals Need Apply: Gender-based Asylum in the U.S. [PDF]
, 2010 Every other year I teach a course entitled The History of Asian Women in America, which focuses on the experiences of East, South and Southeast Asian women as they journey to these shores and resettle.
Takagi, Midori
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Dakwah Dalam Konteks Pluralitas Budaya Lokal [PDF]
, 2007 Islam is religion which is spread out with da 'wa activities. Without that, it would not be as developed as nowadays. In spreading out Islamic teaching to the mad'u, wisdom is really needed. One way to actualize it is by considering the social conditions
Muridan, M. (Muridan)
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
El paradigma tecnológico y la educación del Siglo XXI
Interconectando Saberes, 2016 Las TIC suponen un camino para mejorar la calidad de la educación, existe debate entre si su implementación ha tenido o no un impacto efectivo en mejorar el aprendizaje, as.
Brenda Marina Mártinez Herrera
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Remember the Fillmore: The Lingering History of Urban Renewal in Black San Francisco
, 2012 In the summer of 2008, I moved to San Francisco, California. I lived in the city for three months. As a researcher, my objective was to learn more about Mayor Gavin Newsome’s African-American Out-Migration Task Force.
Jackson, Christina, Jones, Nikki
core