Results 71 to 80 of about 10,853,203 (338)

Thinking Together Digitalization and Social Innovation in Rural Areas: An Exploration of Rural Digitalization Projects in Germany

European Countryside, 2020
Digitalization and social innovation are often discussed separately and without any spatial reference or in relation to cities, although newer works show the importance of social innovation also for rural areas.
Ariane Sept
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Social Capital, Innovation and Growth: Evidence from Europe [PDF]

This paper investigates the interplay between social capital, innovation and economic growth in the European Union. We identify innovation as an important mechanism that transforms social capital into economic growth. In an empirical investigation of 102
Akcomak, Semih, ter Weel, Bas
core   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Short-term acute outcomes by clinical and socioeconomic characteristics in adults with SARS-CoV-2: a population-based cohort study focused on the first two years of the COVID-19 pandemic

Archives of Public Health
Background The COVID-19 pandemic disproportionately affected vulnerable populations in terms of comorbidity and socioeconomic disadvantage, both between and within countries.
Alice Corsaro, Federico Banchelli, Rossella Buttazzi, Enrico Ricchizzi, Carlo Gagliotti, Elisa Fabbri, Elisa Gentilotti, Maurizia Rolli, Evelina Tacconelli, Maria Luisa Moro, Nicola Caranci, Elena Berti   +11 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The current status, challenges, and strategies for high-quality development of the public health system in China

Zhongguo gonggong weisheng
ObjectiveTo systematically evaluate the current status, strengths, and weaknesses of the high-quality development of China’s public health system, and to propose targeted suggestions for improving the system, providing a basis for promoting the high ...
Huihui HUANGFU, Qingyu ZHOU, Huayi ZHANG, Peiyu FENG, Peiwu SHI, Qunhong SHEN, Zhaoyang ZHANG, Zheng CHEN, Chuan PU, Lingzhong XU, Zhi HU, Anning MA, Zhaohui GONG, Tianqiang XU, Panshi WANG, Hua WANG, Chao HAO, Mo HAO, Chengyue LI   +18 more
doaj   +1 more source

Health Biotechnology Innovation for Social Sustainability -A Perspective from China [PDF]

, 2011
China is not only becoming a significant player in the production of high-tech products, but also an increasingly important contributor of ideas and influence in the global knowledge economy.
Chen, Yantai, Ely, Adrian
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Current status of hypertension management operation mechanisms in Chinese mainland and their impact on prevention and control effects: an analysis on official documents

Zhongguo gonggong weisheng
ObjectiveTo evaluate the current status of hypertension prevention and control management operation mechanisms in Chinese mainland, explore the impact of their improvement on hypertension prevention and control effects, and provide a reference for ...
Huihui HUANGFU, Qinwen YU, Peiwu SHI, Qunhong SHEN, Zhaoyang ZHANG, Zheng CHEN, Chuan PU, Lingzhong XU, Zhi HU, Anning MA, Zhaohui GONG, Tianqiang XU, Panshi WANG, Hua WANG, Chao HAO, Qingyu ZHOU, Mo HAO, Chengyue LI   +17 more
doaj   +1 more source