Results 81 to 90 of about 1,058,751 (293)

Assessing the role of the research in the transition to organic farming by using the Actor Network Theory: lessons from two case studies in France and Bulgaria [PDF]

open access: yes, 2018
This paper explores the potential of Actor Network Theory (ANT) in understanding how the process of interaction and translation between human and non-human actors contribute to the development, adoption and diffusion of science-based innovations linked ...
Barjolle, Dominique   +3 more
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

TECHNOLOGIES AND IMPLEMENTATION TOOLS OF SOCIAL INNOVATIONS OF INDUSTRIAL ENTERPRISES

open access: yesВестник Северо-Кавказского федерального университета, 2022
The article examines the possibility of high technologies using to implement social innovations of industrial enterprises. A description of the basic practical technologies and tools for implementing social innovation of industrial enterprises, the use ...
Svetlana Kalyugina
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

What is green Innovation? A quantitative literature review [PDF]

open access: yes
The importance of green innovation management is growing in practice and academia likewise. To our knowledge, a recent and comprehensive literature review is lacking.
Herstatt, Cornelius   +2 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Fostering Community Ownership for Sustainable Social Innovations in Pastoral and Agro-Pastoral Regions

open access: yesChallenges
Social innovation has emerged as a prominent strategy in development practice, attracting substantial scholarly attention. In Ethiopia’s pastoral and agro-pastoral areas, characterized by vulnerability and persistent development challenges, non ...
Mulye Tadesse   +4 more
doaj   +1 more source

Facilitating the take-up of new HCI practices: a ‘diffusion of innovations’ perspective [PDF]

open access: yes, 2013
The workshop Made for Sharing: HCI Stories of Transfer, Triumph & Tragedy focuses on collecting cases in which practitioners have used their HCI methods in new contexts.
Cockton, Gilbert, Vermeeren, Arnold
core  

Autism, the Integrations of 'Difference' and the Origins of Modern Human Behaviour [PDF]

open access: yes, 2009
It is proposed here that the archaeological evidence for the emergence of 'modern behaviour' (160,000-40,000 bp) can best be explained as the rise of cognitive variation within populations through social mechanisms for integrating 'different minds ...
Spikins, Penny
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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