Results 91 to 100 of about 8,448,369 (354)

Social isolation during the COVID-19 pandemic can increase physical inactivity and the global burden of cardiovascular disease

American Journal of Physiology. Heart and Circulatory Physiology, 2020
Emerging data indicate a substantial decrease in global physical activity levels during the period of social isolation adopted worldwide to contain the spread of the coronavirus disease 2019 (COVID-19).
T. Peçanha, K. Goessler, H. Roschel, B. Gualano   +3 more
semanticscholar   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

FEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman, Annika Egeler, Saskia Rödl, Johannes M. Herrmann   +3 more
wiley   +1 more source

Effects of short-term isolation on social behaviors in prairie voles.

PLoS ONE
Social isolation affects the brain and behavior in a variety of animals, including humans. Studies in traditional laboratory rodents, including mice and rats, have supported the idea that short-term social isolation promotes affiliative social behaviors,
Jesus E Madrid, Nicole M Pranic, Samantha Chu, Johanna J D Bergstrom, Rhea Singh, Joclin Rabinovich, Kaycee Arias Lopez, Alexander G Ophir, Katherine A Tschida   +8 more
doaj   +1 more source

Post-weaning social isolation alters sociability in a sex-specific manner

Frontiers in Behavioral Neuroscience
Adolescence is a critical period for brain development in humans and stress exposure during this time can have lasting effects on behavior and brain development.
Teneisha Myers, Elizabeth A. Birmingham, Brigham T. Rhoads, Anna G. McGrath, Nylah A. Miles, Carmen B. Schuldt, Lisa A. Briand, Lisa A. Briand   +7 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Neighborhood social cohesion and physical disorder in relation to social isolation in older adults: racial and ethnic differences

BMC Public Health
Background Neighborhood factors of social isolation have been understudied, hindering efforts to reduce social isolation at the neighborhood level. This study aims to investigate the longitudinal effects of neighborhood social cohesion and physical ...
Weidi Qin, Emily J. Nicklett, Jiao Yu, Ann W. Nguyen   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

GAMBARAN KEMAMPUAN INTERAKSI SOSIAL PASIEN ISOLASI SOSIAL SETELAH PEMBERIAN SOCIAL SKILLS THERAPY DI RUMAH SAKIT JIWA

Jurnal Ilmiah Kesehatan, 2018
Social isolation is one of the nursing diagnoses that can be established in patients who are symptomatic to withdraw, withdraw from social activities and do not want to interact with others even with nurses.
Sukma Ayu Candra Kirana
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Association Between Ego-Resilience and Social Isolation Among Urban Older People

Gerontology and Geriatric Medicine
Social isolation among older adults affects their physical and mental health. Ego-resilience is associated with flexible adaptation to various environments and acceptable behaviors.
Kazuaki Hashimoto MD, PhD, Takeaki Takeuchi MD, PhD, Kazushige Ihara MD, PhD, Shuichi Obuchi PT, PhD, Hisashi Kawai PhD, Hirohiko Hirano DDS, PhD, Yoshinori Fujiwara MD, PhD, Kim Hunkyung PhD, Yutaka Watanabe DDS, PhD, Masahiro Hashizume MD, PhD   +9 more
doaj   +1 more source