Results 101 to 110 of about 1,524,576 (347)

Strengthening Social Capital to Address Isolation and Loneliness in Long-Term Care Facilities During the COVID-19 Pandemic: Systematic Review of Research on Information and Communication Technologies [PDF]

, 2023
Idrissa Beogo, Drissa Sia, Stéphanie Collin, Andi Phaelle Gedeon, Michaël-Christopher Louismé, Jean Ramdé, Marie‐Pierre Gagnon, Éric Tchouaket Nguemeleu   +7 more
openalex   +1 more source

Economic Isolation, Inequality, and the Suits Index of Progressivity [PDF]

We present a class of social evaluation functions and inequality indices that obey standard axioms of welfare economics and that can be intuitively linked to measures of relative deprivation and economic isolation.
DUCLOS, Jean-Yves
core  

The Psychological Impact of Long-Term Solitary Confinement on Inmates in the United States [PDF]

, 2016
Psychological distress among inmates is prevalent in correctional facilities throughout the United States. Although, according to Haney (2003), severe isolation of incarcerates has been commonplace in prisons since their inception, the use of secure ...
Schulz, Kerri
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Using machine learning to understand social isolation and loneliness in schizophrenia, bipolar disorder, and the community

Schizophrenia
Social disconnection, including objective social isolation and subjective loneliness, is linked to substantial health risks. Yet, little is known about the predictors of social disconnection in individuals with mental illness.
Samuel J. Abplanalp, Michael F. Green, Jonathan K. Wynn, Naomi I. Eisenberger, William P. Horan, Junghee Lee, Amanda McCleery, David J. Miklowitz, L. Felice Reddy, Eric A. Reavis   +9 more
doaj   +1 more source

“I Am Actually Scared of Everyone”: Older Adults’ Experiences of Social Isolation during COVID-19: A Qualitative Systematic Review

COVID
The emergence of the coronavirus COVID-19 in December 2019 in Wuhan, China, affected all facets of people’s lives worldwide. As a result of the severity of the pandemic, governments worldwide adopted several policies and containment measures, such as ...
Oladapo Akinlotan, Aishatu Jalo
doaj   +1 more source

Parvalbumin Interneurons and Perineuronal Nets in the Hippocampus and Retrosplenial Cortex of Adult Male Mice After Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment [PDF]

, 2021
Patrycja Klimczak, Arianna Rizzo, Esther Castillo-Gómez, Marta Pérez-Rando, Yaiza Gramuntell, M.a Carmen Salcedo Beltrán, Juan Nácher   +6 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Social Isolation and Depression among Elderly from an Indian Urban Slum Population

Journal of the Indian Academy of Geriatrics
Background: The aim of the study was to understand the reported prevalence of subjective, objective social isolation, marginal family, and marginal friendship ties in relation to each other.
Mohan Kumar, Manisha Ruikar, V. L. Surya
doaj   +1 more source