Results 61 to 70 of about 8,448,369 (354)
Covid-19: isolamento social e suas consequências / Covid-19: social isolation and its consequences [PDF]
, 2021 Tarcísio Correia Sposito +5 more
openalex +1 more source
Pet ownership, loneliness, and social isolation: a systematic review
Social Psychiatry and Psychiatric Epidemiology, 2022 Several publications explored a relationship between pet ownership and lower levels of loneliness and social isolation. However, to the best of our knowledge, no systematic review has yet synthesized the evidence on these associations.
B. Kretzler, H. König, A. Hajek
semanticscholar +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Social isolation and the brain: effects and mechanisms
Molecular Psychiatry, 2022 An obvious consequence of the coronavirus disease (COVID-19) pandemic is the worldwide reduction in social interaction, which is associated with many adverse effects on health in humans from babies to adults.
Ying Xiong +3 more
semanticscholar +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
BMC GeriatricsBackground Social isolation poses a significant threat to the health of older adults. However, there has been a lack of attention to the relationship between Internet use and social isolation.
Qiyuan Huang +8 more
doaj +1 more source
Social isolation induces hyperactivity and exploration in aged female mice.
PLoS ONE, 2021 Prolonged social isolation is associated with poor physical and mental health outcomes, findings observed in both humans, and rodent models of isolation.
D Gregory Sullens +5 more
doaj +1 more source
Social isolation and loneliness among older adults in the context of COVID-19: a global challenge
Global Health Research and Policy, 2020 We are experiencing a historical moment with an unprecedented challenge of the COVID-19 global pandemic. The outbreak of COVID-19 will have a long-term and profound impact on older adults’ health and well-being. Social isolation and loneliness are likely
Bei Wu
semanticscholar +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
BMJ Open, 2020 Objective This study explored UK public perceptions and experiences of social distancing and social isolation related to the COVID-19 pandemic. Design This qualitative study comprised five focus groups, carried out online during the early stages of the ...
S. Williams +3 more
semanticscholar +1 more source