Results 61 to 70 of about 1,514,946 (349)
Influence of Maternal Care on Behavioural Development of Domestic Dogs (Canis Familiaris) Living in a Home Environment [PDF]
, 2017 Maternal care has been shown to affect the development of the brain, behaviour, social skills and emotional systems of the young of many mammalian species including dogs.
Ainsworth +6 more
core +4 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Scientific ReportsFrailty, social isolation, and loneliness have individually been associated with adverse health outcomes. This study examines how frailty in combination with loneliness or social isolation is associated with socioeconomic deprivation and with all-cause ...
Marina Politis +7 more
doaj +1 more source
Isolation and social instigation in animal models of aggression: effects of an mGLU1 receptor antagonist administration [PDF]
, 2017 Isolate-induced aggression in male mice is a model widely used in psychoparmacology of aggression. Animals are usually isolated for 30 days and subsequently treated and confronted with an anosmic opponent in a neutral area.
Martin-Lopez, Maria Mercedes
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Scientific ReportsAdolescent social interactions are essential for shaping adult behavior in humans. While rodent studies have highlighted the impact of social isolation on behavior, many extend isolation into adulthood, making it challenging to pinpoint the long-term ...
Michelle Kim +3 more
doaj +1 more source
Perceived Social Isolation and Outcomes in Patients With Heart Failure
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 BackgroundPerceived social isolation has been shown to have a negative impact on health outcomes, particularly among older adults. However, these relationships have not been fully examined among patients with heart failure.
Sheila M. Manemann +10 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Effects of short-term isolation on social behaviors in prairie voles.
PLoS ONESocial isolation affects the brain and behavior in a variety of animals, including humans. Studies in traditional laboratory rodents, including mice and rats, have supported the idea that short-term social isolation promotes affiliative social behaviors,
Jesus E Madrid +8 more
doaj +1 more source
Post-weaning social isolation alters sociability in a sex-specific manner
Frontiers in Behavioral NeuroscienceAdolescence is a critical period for brain development in humans and stress exposure during this time can have lasting effects on behavior and brain development.
Teneisha Myers +7 more
doaj +1 more source