Results 121 to 130 of about 1,009,104 (310)

Development of the Integrated Model of the Automotive Product Quality Assessment [PDF]

, 2017
Issues on building an integrated model of the automotive product quality assessment are studied herein basing on widely applicable methods and models of the quality assessment.
Amineh, H. (Hadi), Kosach, N. (Nataliya)
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Performance indicators for roadway bridges [PDF]

, 2016
Publicado em "Maintenance, monitoring, safety, risk and resilience of bridges and bridge networks". ISBN 978-1-138-02851-7The performance indicators should, by its definition, allow capturing the life-cycle degradation processes affecting maintenance ...
Dengg, F., Matos, José C., Strauss, A., Tanasic, N., Vidovic, A., Zambon, I.   +5 more
core  

Social Life Cycle Assessment of Batteries

AbstractAs the demand for batteries is continuously increasing, understanding their social implications becomes increasingly important.This chapter points out the relevance of the social life cycle assessment (SLCA) to evaluate the effects on social issues of battery throughout its entire life cycle, from raw material extraction to disposal.In the ...
Maurizio Cellura, Anna Irene De Luca, Nathalie Iofrida, Marina Mistretta   +3 more
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Social life cycle assessment: a systematic review from the engineering perspective

International Journal of Sustainable Engineering
Social Life Cycle Assessment (SLCA) has emerged as a crucial element in sustainability discussions, gaining traction in academic research and industry practices.
Yagmur Atescan Yuksek, Yousef Haddad, Rylan Cox, Konstantinos Salonitis   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Monetizing Social Life Cycle Assessment (SLCA): A Case Study in SMEs Tapioca Industry in Lampung, Indonesia

Applied Environmental Research
To verify the responsible and sustainable functioning of circular economy (CE), assessing the sustainability of CE methods is essential. The consistent absence of a social aspect within the CE has been a recurring topic in research.
yosep, Unang Mulkhan, Udin Hasanudin, Dewi Agustina Iryani   +3 more
doaj   +1 more source

A culturally-focused life cycle sustainability assessment: Analysis of forestry value chain options with Māori land owners : A thesis presented in partial fulfilment of the requirements of Doctor of Philosophy in Life Cycle Management At Massey University, Palmerston North, New Zealand [PDF]

, 2016
The purpose of this research was to 1) explore the potential for the more distinctive representation of Māori culture in Life Cycle Sustainability Assessment (LCSA), and 2) understand the relationship between culturally-focused LCSA and the Māori ...
Pizzirani, Stefania Maria
core