Results 81 to 90 of about 28,036,793 (273)

Social Media Activism

This book focuses on the referendums against water privatization in Italy and explores how activists took to social media, ultimately convincing twenty-seven million citizens to vote.
Cernison, Matteo
core   +1 more source

An Overview of Information Overload, System Feature Overload, Social Overload and Communication Overload [PDF]

Social media has faced difficulties in recent years due to users ceasing to use them, but little is known about the relationships between the various aspects of overload and how this negatively impacts users' social media exhaustion.
Tuan Besar, Tuan Badrol Hisham, Abdull Malek, Siti Nadia Nadirah, Noor Azri, Muhammad Danish   +2 more
core   +1 more source

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

Advanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang, Qiyue Zhang, Yueyang Qiu, Haocheng Suo, Zengqian Liu, Bing Bai, Qiang Wang, Qing Zhou   +7 more
wiley   +1 more source

Breaking the boredom-fatigue cycle: How algorithmic awareness protects against social media exhaustion

Acta Psychologica
This study examines how boredom proneness and information overload contribute to social media fatigue among digitally native young adults (aged 18–30), and how algorithmic media content awareness (AMCA) moderates these relationships.
Aakash Kamble, Karabi Bhattacharya Rao, Ajinkya Navare   +2 more
doaj   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Fatigue in the Virtual World: The Impact of Intrinsic Motivation and External Pressures on Young Vietnamese Users’ Intentions to Switch Social Media Platforms

SAGE Open
This study investigates the psychological factors influencing users’ intention to switch social media platforms in the context of an increasingly overloaded digital environment.
Tuan Hai Nguyen
doaj   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Exploring discontinuous intentions of social media users: a cognition-affect-conation perspective

Frontiers in Psychology
IntroductionDrawing on the cognition-affect-conation (C-A-C) framework, this study investigates how perceived information and social and system feature overload induce depression and anxiety, which leads to affect discontinuous intentions of the social ...
Sara Qaisar, Anum Nawaz Kiani, Afsheen Jalil   +2 more
doaj   +1 more source

Participation in Social Media: Studying Explicit and Implicit Forms of Participation in Communicative Social Networks [PDF]

, 2016
The diverse forms of participation in social media raise many methodological and ethical issues that should be acknowledged in research. In this paper, participation in social media is studied by utilising the framework of explicit and implicit ...
Janne Matikainen, Matikainen, Janne, Mikko Villi, Villi, Mikko   +3 more
core   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source