Results 111 to 120 of about 8,861,571 (318)

Elementos históricos e filosóficos para a crítica da epidemiologia

open access: yesRevista de Saúde Pública
Objetivou-se identificar as bases históricas e filosóficas da epidemiologia, a fim de enriquecer a reflexão sobre a inserção dessa ciência no conjunto das práticas de saúde.
José Ricardo de C. M. Ayres
doaj  

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Socio-economic models of divorces in different societies [PDF]

open access: yesApplications of mathematics in biology and medicine, Krynica Morska, 23-27.09.2012, 2012
Population dynamic of getting divorced depends on many global factors, including social norms, economy, law or demographics as well as individual factors like the level of interpersonal or problem-solving skills of the spouses. We sought to find such a relationship incorporating only quantitative variables and test theoretical model considering phase ...
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Pensamento clássico da saúde pública paulista na era dos centros de saúde e educação sanitária

open access: yesRevista de Saúde Pública
Revisão histórica sobre ideias e conceitos da organização sanitária que se seguiram à introdução do modelo do Centro de Saúde distrital pela reforma do Serviço Sanitário em 1925.
Guilherme Arantes Mello
doaj  

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

SOCIAL USES OF MEDICINE [PDF]

open access: yesAmerican Journal of Public Health, 1920
Seventy percent of our people need medical or dental treatment, but go without because of lack of proper medical organization. Dr. Armstrong is not merely critical, but is constructive. He shows the absurdity of making physicians dependent on sickness for support, and outlines a plan of community procedure on a rational basis.
openaire   +3 more sources

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