Results 141 to 150 of about 3,477,145 (304)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Health and society. Contributions of Latin American Perspectives

open access: yesSocial Medicine, 2006
The paper deals with the history of Latin America and the development of sociology and social medicine thought it. It makes a balance of the emergence and contributions of this innovative thinking.
Oliva López Arellano   +1 more
doaj  

Nurses Alumni Association Bulletin, Fall 2001 [PDF]

open access: yes, 2001
2001 - 2002 Meeting Date Calendar 2002 Annual Luncheon & Meeting Notice Bulletin Publication Committee, Officers and Committee Chairs The President\u27s Message Treasurer\u27s Financial Report Auditor\u27s Financial Report Alumni Scholarship Fund Resume ...
Caruso, Joan   +5 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

The Economic Crisis and Public Health

open access: yesSocial Medicine, 2009
The current global economic crisis seriously threatens the health of the public. Challenges include increases in malnutrition; homelessness and inadequate housing; unemployment; substance abuse, depression, and other mental health problems; mortality ...
Barry S. Levy, Victor W. Sidel
doaj  

The role of social medicine in the COVID-19 pandemic era. [PDF]

open access: yesJ Glob Health, 2021
Bubbico L   +3 more
europepmc   +1 more source

Country Profile on Disability: Republic of Uzbekistan [PDF]

open access: yes, 2002
[Excerpt] The Law on Social Security of Disabled People in the Republic of Uzbekistan, Article 1 defines a person with disability as one who is in need of aid because he/she has physical or mental problems. Daily activities such as moving, orientation,
Japan International Cooperation Agency
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

More than just meds: National survey of providers’ perceptions of patients’ social, economic, environmental, and legal needs and their effect on emergency department utilization

open access: yesSocial Medicine, 2014
Introduction: Emergency departments (EDs) are the safety net for millions of patients who need to access care. Many of these patients have social needs that may influence their healthcare.
Lia ilona Losonczy   +4 more
doaj  

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