Results 141 to 150 of about 12,155,964 (381)

Medicine Infected by Politics: The American Occupation of Haiti, 1915-1934 [PDF]

open access: yes, 2019
This article discusses the impact that politics and social beliefs have on the humanitarian goals of medicine, using the American occupation of Haiti (1915-1934) as a backdrop.
Scherr, Cooper
core   +2 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Is social capital associated with health ? Evidence from a study on the elderly italians [PDF]

open access: yes, 2016
In the last decades there had been undoubted improvements in medicine and living conditions, still the distribution of health within and between regions is facing an increasing unbalance and many researchers from different fields have tried to understand
AREZZO, Maria Felice
core  

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Nurses Alumni Association Bulletin, Fall 2001 [PDF]

open access: yes, 2001
2001 - 2002 Meeting Date Calendar 2002 Annual Luncheon & Meeting Notice Bulletin Publication Committee, Officers and Committee Chairs The President\u27s Message Treasurer\u27s Financial Report Auditor\u27s Financial Report Alumni Scholarship Fund Resume ...
Caruso, Joan   +5 more
core   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

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