Results 91 to 100 of about 2,523,136 (241)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Social enterprise as a socially rational business [PDF]

open access: yes, 2006
What is the goal of social enterprise policy? Is it the creation of a ‘not-for-profit’ or ‘more-than-profit’ business movement? In institutional policy circles, arguments are shaped by the desire to protect assets for the community, while entrepreneurial
Ridley-Duff, R.
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Les militants-internautes

open access: yesCommunication, 2003
Investing firstly in a timely fashion, during periods of intense mobilization, the potential of communication linked to electronic messaging, French social movement have also constructed more perennial digital interfaces (web sites, listservs, etc.) and ...
Fabien Granjon
doaj   +1 more source

The Unhappy Marriage of Theory and Practice: An Analysis of a Battered Women\u27s Shelter [PDF]

open access: yes, 1988
Focuses on the role of battered women\u27s shelters in the U.S. as a response to the problem of violence against women in society. Examination of the battered women\u27s movement and the shelters the movement has spawned; Contradictions between feminist ...
Murray, Susan B
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Civil Rights 3.0 [PDF]

open access: yes, 2014
It is now commonplace to hear the LGBT rights movement being described as the last, or the next, or today’s, pre-eminent civil rights issue. This chapter will explore what that means from several perspectives: What does the label tell us about the civil ...
Hunter, Nan D.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Efektivitas Kebijakan Sosial dalam Pemecahan Masalah Sosial

open access: yesJSP: Jurnal Ilmu Sosial dan Ilmu Politik, 2011
Social policy was understood as a response of government toward social problems steam from individuals and systems, as well as social structures and social institutions.
- Soetomo
doaj   +1 more source

Cultural evolution and prosociality: widening the hypothesis space [PDF]

open access: yes, 2016
Norenzayan and colleagues suggest that Big Gods can be replaced by Big Governments. We examine forms of social and self-monitoring and ritual practice that emerged in Classical China, heterarchical societies like those that emerged in pre-Columbian ...
Huebner, Bryce, Sarkissian, Hagop
core  

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