Results 101 to 110 of about 2,523,136 (241)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Translational Exercise BiomedicineTo assess the feasibility of methods and estimate the potential effect of interrupting sedentary behaviour, with intermittent or continuous physical activity breaks, on cognitive performance in young people with Cerebral Palsy.
Coe Shelly +15 more
doaj +1 more source
A systematic review on the role of therapist characteristics in the treatment of eating disorders
Research in PsychotherapyTreating patients with eating disorders can be challenging for therapists, as it requires the establishment of a strong therapeutic relationship. According to the literature, therapist characteristics may influence intervention outcomes. The aim of this
Gaia Albano +5 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Discourses and Conditions of Possibility in Latin American Social Movements: The Cases of the Bolivian 'Water War' and the Movement of Opposition against the New Airport in Mexico City [PDF]
This work presents a comparative analysis of two Latin American social movements. The first case is the movement of opposition against the privatisation of water and sanitation services (WSS) in Cochabamba, Bolivia and the second case is the movement of ...
J Carlos Dominguez (QEH)
core
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Making Change: How Social Movements Work and How to Support Them [PDF]
, 2009 Provides guidance for funders and activists on funding and sustaining a successful social movement. Details key elements of success, organizational capacities that need to be developed, areas for effective foundation investment, and issues to ...
Manuel Pastor, Rhonda Ortiz
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The Prerequisites for Independent Living [PDF]
, 1984 [Excerpt] Independent Living is a term that was coined in the 1960s by the American disability movement. Today it has become a buzz word frequently used and abused by consumers and professionals alike.
Ratzka, Adolf
core +1 more source