Results 141 to 150 of about 663,468 (311)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

The effect of Network Position and relationship quality on organizational performance- The case of ABW Family

open access: yes, 2012
全文[[abstract]]The interactions among firms varied by their network positions they were influenced. Our concern is to consider the relationship among network position, relationship quality, organizational learning and organizational performance.
Lin, Chih-Wei, Lee, Ting-Lin
core  

Social network analysis shows direct evidence for social transmission of tool use in wild chimpanzees

open access: yes, 2014
The authors are grateful to the Royal Zoological Society of Scotland for providing core funding for the Budongo Conservation Field Station. The fieldwork of CH was funded by the Leverhulme Trust, the Lucie Burgers Stichting, and the British Academy.
Zuberbühler, Klaus   +16 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Reliable online social network data collection

open access: yes, 2012
Large quantities of information are shared through online social networks, making them attractive sources of data for social network research. When studying the usage of online social networks, these data may not describe properly users’ behaviours.
Parris, Iain   +5 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Detecting Change in Longitudinal Social Networks [PDF]

open access: yesJournal of Social Structure, 2011
Ian McCulloh, Kathleen M. Carley
doaj   +1 more source

Assessing a Sport/Cultural Events Network: An Application of Social Network Analysis

open access: yes, 2009
The purpose of this study was to assess the complexity of a sport/cultural events network. To that intent, a social network analysis was conducted in a small community in the US.
Costa, CA, Ziakas, V
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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