Results 51 to 60 of about 46,456 (291)
A community based approach for managing ontology alignments [PDF]
, 2008 The Semantic Web is rapidly becoming a defacto distributed repository for semantically represented data, thus leveraging on the added on value of the network effect.
Correndo, Gianluca +2 more
core
, 2013 This paper describes the Massive Ontology Interface (MOI), a web portal which facilitates interaction with a large ontology (over 200,000 concepts and 1.6M assertions) that is built automatically using OpenCyc as a backbone.
Sarjant, Samuel +5 more
core +1 more source
A fast and economic ontology engineering approach towards improving capability matching : application to an online engineering collaborative platform [PDF]
, 2014 Fulfilling needs through internal and external resources is a key business requirement. To better enable this, description of both needs and resources, using a common domain language is required.
Bal, Jay +5 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Masculinity and Man’s Problems in Presentations of Contemporary Young People [PDF]
Journal of Interdisciplinary Sciences, 2019 This study is conducted from the standpoint of the modern interdisciplinary direction in social sciences - boyhood studies – that initiates the necessity of studying the ideas of modern youth about masculinity and specific male and youth problems in ...
Ekaterina Khitruk
doaj
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Journal of Social Ontology, 2021 This paper pursues a naturalist endeavor in social ontology by arguing that the Beliefs-Rules-Equilibrium account of institutions can help to advance the debate over the nature of social kinds.
Hédoin Cyril
doaj +1 more source
Ontology engineering in virtual breeding environments
, 2007 This paper proposes a new method for managing the use of ontologies in the context of a Virtual Breeding Environment. This research work focus is on the dissolution phase of a Virtual Enterprise or Collaborative Network, whereontology segmentation ...
Lucas Soares, António +9 more
core +1 more source
A model-based approach to social ontology [PDF]
, 2022 This paper argues for theoretical modeling and model-construction as central (but not necessarily the only) types of activities that philosophers of social ontology (in the analytic tradition) engage in.
Sarkia, Matti
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source