Results 51 to 60 of about 32,178 (248)
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
“Is logic a physical variable?” Introduction to the Special Issue
Zagadnienia Filozoficzne w Nauce, 2020 “Is logic a physical variable?” This thought-provoking question was put forward by Michael Heller during the public lecture “Category Theory and Mathematical Structures of the Universe” delivered on 30th March 2017 at the National Quantum Information ...
Michał Eckstein, Bartłomiej Skowron
doaj
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Causal powers and social ontology [PDF]
Synthese, 2018 Over the last few decades, philosophers and social scientists have applied the so-called powers ontology to the social domain. I argue that this application is highly problematic: many of the alleged powers in the social realm violate the intrinsicality condition, and those that can be coherently taken to be intrinsic to their bearers are arguably ...
openaire +2 more sources
Ontology Merging as Social Choice [PDF]
, 2011 The problem of merging several ontologies has important applications in the Semantic Web, medical ontology engineering, and other domains where information from several distinct sources needs to be integrated in a coherent manner. We propose to treat ontology merging as a problem of social choice, i.e., as a problem of aggregating the input of a set of
PORELLO D, ENDRISS U
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IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Journal of Social OntologyThis is a paper about the role of value in projects in social ontology. In it, I do three things: first, I argue that much like work in mainstream metaphysics, values play a central role in projects in social ontology.
Dee Payton
doaj +1 more source
Social Ontology and Immanent Realism
Phenomenology and Mind, 2016 What are the intentional objects of groups’ beliefs? This paper claims that they are immanent facts, i.e., facts which exist only within groups’ minds. Since in relevant literature the notion of immanent object and the related theory of “immanent realism”
Alessandro Salice
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Abstract Is money an object? Although paper money is naturally regarded as a material or concrete object, this characterization does not hold for electronic money. John Searle maintains that institutional statuses, such as those of money and property, are imposed on concrete objects. But he regards electronic money as an exception.
openaire +1 more source