Results 61 to 70 of about 7,916,499 (329)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Masculinity and Man’s Problems in Presentations of Contemporary Young People [PDF]
Journal of Interdisciplinary Sciences, 2019 This study is conducted from the standpoint of the modern interdisciplinary direction in social sciences - boyhood studies – that initiates the necessity of studying the ideas of modern youth about masculinity and specific male and youth problems in ...
Ekaterina Khitruk
doaj
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Journal of Social Ontology, 2021 This paper pursues a naturalist endeavor in social ontology by arguing that the Beliefs-Rules-Equilibrium account of institutions can help to advance the debate over the nature of social kinds.
Hédoin Cyril
doaj +1 more source
Dealing with elements of medical encounters: An approach based on ontological realism [PDF]
, 2016 Electronic health records (EHRs) serve as repositories of documented data collected in a health care encounter. An EHR records information about who receives, who provides the health care and about the place where the encounter happens.
Fernanda, Farinelli +3 more
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Should Bitcoin Be Classified as Money?
Journal of Social Ontology, 2021 The advent of virtual currencies such as bitcoin raises a pressing question for lawmakers, regulators, and judges: should bitcoin and other virtual currencies be classified as money or currency for legal and regulatory purposes?
Passinsky Asya
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Journal of Social Ontology, 2021 Teleological thinking about money reasons from what money is for to both how it ought to be used and what forms it should take. One type, found in Aristotle’s argument against usury, takes teleological considerations alone to decisively settle normative ...
Dick David G.
doaj +1 more source
Ontology Merging as Social Choice [PDF]
, 2014 The problem of merging several ontologies has important applications in the Semantic Web, medical ontology engineering and other domains where information from several distinct sources needs to be integrated in a coherent manner.We propose
Endriss, Ulle, Porello, Daniele
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