Results 71 to 80 of about 1,251,629 (312)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A Prospective Audit Investigating How the Anticholinergic Effect of Medications on Cognition Is Assessed and Reduced in Patients Admitted to an Older Adult Ward in a Psychiatric Hospital

BJPsych Open
Aims: Older adults often have multiple comorbidities associated with an increased risk of anticholinergic effects. Mental health medications increase this risk, contributing to cognitive decline, dementia, memory loss and confusion.
Dinushi Marambe, Prami Rai
doaj   +1 more source

Social partnership in the system of social and labour relations of the hotel and restaurant economy [PDF]

, 2017
У статті розглянуто поняття соціального партнерства в системі соціально-трудових відносин готельно-ресторанного господарства. Розглянуті форми соціального партнерства. Розкриті принципи соціального партнерства.
Фальченко, Олена Олександрівна
core  

Local status and power in area-based health improvement partnerships [PDF]

, 2014
This is the authors' PDF version of an article published in Health© 2014. The definitive version is available at http://hea.sagepub.comArea-based initiatives (ABIs) have formed an important part of public policy towards more socio-economically deprived ...
Bartlett D, Berkeley D, Bradford N, Carlisle S, Charmaz K, Department for Communities and Local Government, Department of Health, Department of Health, Elias N, Elias N, Elias N, Elias N, Elias N, Elias N, Lawless P, National Institute for Health and Clinical Excellence, Pawson R, Stewart M, Strauss AL, Unwin J, Yin RK   +20 more
core   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Supporting Non-Psychiatric Trainees to Engage with Reflective Practice and Attend to Their Wellbeing Through Balint Group

BJPsych Open
Aims: Doctors in training report high rates of burnout. The Balint group lends itself to addressing emotional stress and hence the associated risk of burnout. However, Balint group attendance among GP trainees and foundation doctors locally has been poor
Ayatalla Gabre, Elinor Bradley
doaj   +1 more source

Evaluating the impact of the report "Faithful Cities" on the Church of England's role in urban regeneration: case study in two Dioceses (Birmingham and Worcester) [PDF]

, 2011
The Church of England's approach to urban regeneration has been shaped by government-led regeneration and its own social, political and financial situation, rather than its theology.
Atfield, Tom David
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Introducing the Dementia Crisis Service in East Kent: Can We Reduce Rates of Hospital Admission?

BJPsych Open
Aims Admissions to hospital can be traumatic for a person with dementia due to an inability to cope with unfamiliar environments, faces and routines.
Swarupa SriBalaskanda, Bastiaan Veugelers   +1 more
doaj   +1 more source

Verité Update, vol.2: Clear Voice [PDF]

, 2008
This issue of Verite Update announces a new partnership with Clear Voice hotline service, an independent social enterprise that offer workers a mechanism through which to express grievances, reveal mistreatment, and talk about conditions with an ...
Verité
core   +1 more source