Results 91 to 100 of about 293,038 (290)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
ANALYSING MACEDONIAN TRANSLATIONS OF ENGLISH TERMS RELATED TO SOCIAL PATHOLOGY
, 2018 The paper deals with the analysis of Macedonian translations of several English words/expressions in the field of social pathology. The authors designed a questionnaire containing English words/expressions related to social pathology and distributed ...
Gerasimoski, Sase, Trajkovska, Vesna
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Causes and manifestations of social pathology
, 2004 With the growth of societies in size, complexity and diversification, the obtaining formal and informal factors of social control become insufficient, which contributes to the rise of social pathology. The paper contains an overview of definitions of the
Dobieszewski, Adolf
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 1993 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis investigates what can be gained by approaching social work reports and conversations as narratives.
Hall, Christopher J, Hall, C.J
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Critical Theory and Social Pathology [PDF]
, 2018 This Chapter presents an analysis of the idea of social pathology and its role in Frankfurt School Critical Theory. I suggest that this idea can set Critical Theory apart from mainstream liberal approaches, but also note the challenges involved in doing ...
Freyenhagen, Fabian
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Ageism as social pathology in geriatric medicine
, 2023 The main trend of modern geriatrics is to maintain a high functional ability, which consists of intrinsic capacity and environment. It is important to attach importance to the impact of the environment, including of its social component, when can promote
Kiryl, Prashchayeu, Andrei, Ilnitski
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Sickle Cell Disease: A Review Article on Social Pathology, Social Determinants, and Poverty
CasteSickle cell disease (SCD) is a complex genetic condition intertwined with social justice issues. Despite continuous medical advancements, addressing the deep-seated disparities and historical inequalities that disproportionately affect marginalized ...
Sunil Khaparde
doaj +1 more source