Results 111 to 120 of about 296,086 (336)
Sickle Cell Disease: A Review Article on Social Pathology, Social Determinants, and Poverty
CasteSickle cell disease (SCD) is a complex genetic condition intertwined with social justice issues. Despite continuous medical advancements, addressing the deep-seated disparities and historical inequalities that disproportionately affect marginalized ...
Sunil Khaparde
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Non-Suicidal Self-Injury and Indirect Self-Harm Among Danish High School Students [PDF]
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, 2014 Bo Møhl, Peter la Cour, Annika Skandsen
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The Role of Social Media in the Spread of Religious Extremism and its Impact on Social Pathology [PDF]
Social media has played an increasingly significant role in facilitating the spread of religious extremism. This research aims to investigate the role of social media in the spread of religious extremism and its impact on social pathology.
Imammi, Anggun Annisa, Saputra, Rahmat
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Flattery Harm in Social Interactions and its Pathology from Imam Ali’s Viewpoint
پژوهش در دین و سلامت, 2019 For downloading the full-text of this article please click here. Background and Objective: The issue of flattery and its individual and social consequences are regarded as a moral vice in many human societies and the higher degree of this trait in the ...
Omid Ebrahimi +2 more
doaj
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source