Results 101 to 110 of about 293,038 (290)
Humanitarian competencies of a doctor (cardiologist)
The article reveals the features of working with the patient as a social and psychological subject, who, in addition to somatic pathology, has an experience of the disease situation.
E. O. Taratukhin
doaj +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The increasing interest on architectural heritage associated to the recognised building value, at economic, social and cultural levels have stimulated, in the recent decades, the urban rehabilitation and renovation o several cities in Europe.
Silva, J. A. R. Mendes da +2 more
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Non-Suicidal Self-Injury and Indirect Self-Harm Among Danish High School Students [PDF]
Bo Møhl, Peter la Cour, Annika Skandsen
doaj +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Flattery Harm in Social Interactions and its Pathology from Imam Ali’s Viewpoint
For downloading the full-text of this article please click here. Background and Objective: The issue of flattery and its individual and social consequences are regarded as a moral vice in many human societies and the higher degree of this trait in the ...
Omid Ebrahimi +2 more
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Background: Participation is a multidimensional experience influenced by personal, interpersonal, socio-cultural and environmental factors. Currently, relatively little literature exists that explores the roles and experiences of parents as they ...
Edwards, Ann +2 more
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This dissertation entitled “Pathology and Social Media” examines the effects of social media on young minds. In the thesis, I have tried to ascertain whether there is a causal link between the uses of social media and the development of pathological ...
Korgaard, Freja Præst
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