Results 121 to 130 of about 8,064,509 (338)
The use of wearable technology to measure and support abilities, disabilities and functional skills in autistic youth: a scoping review [PDF]
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, 2020 Melissa H. Black +9 more
doaj +1 more source
Consensus and disagreement: the role of quantized behaviours in opinion dynamics [PDF]
arXiv, 2016 This paper deals with continuous-time opinion dynamics that feature the interplay of continuous opinions and discrete behaviours. In our model, the opinion of one individual is only influenced by the behaviours of fellow individuals. The key technical difficulty in the study of these dynamics is that the right-hand sides of the equations are ...
arxiv
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
Contribution of lipophilicity to the clinical effects of drugs
Российский кардиологический журналThe article is devoted to a detailed analysis of the action of various drugs used in the treatment of hypertension and atherogenic dyslipidemia, depending on their ability to dissolve in fatty media (lipophilicity). The authors analyze connection between
A. S. Skotnikov +3 more
doaj +1 more source
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Animal Models of Social Stress: Implications for the Study of Stress Related Pathologies in Humans [PDF]
, 2002 Andrea Sgoifo, Peter Meerlo
openalex +1 more source
Social Pathology of Dementia [PDF]
Archives in Neurology & Neuroscience, 2021 openaire +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source