Results 121 to 130 of about 8,715,620 (378)
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Humanitarian competencies of a doctor (cardiologist)
Российский кардиологический журнал, 2019 The article reveals the features of working with the patient as a social and psychological subject, who, in addition to somatic pathology, has an experience of the disease situation.
E. O. Taratukhin
doaj +1 more source
Extending Honneth’s Shift in Focus for Critical Theory [PDF]
, 2016 Axel Honneth has called for a change of focus in Critical Theory "from the self-generated independence of systems to the damage and distortion of social relations of recognition." I argue that Honneth does not shift his methodological focus ...
Giles, Douglas
core
Earliest Porotic Hyperostosis on a 1.5-Million-year-old Hominin, olduvai gorge, Tanzania. [PDF]
, 2012 Meat-eating was an important factor affecting early hominin brain expansion, social organization and geographic movement. Stone tool butchery marks on ungulate fossils in several African archaeological assemblages demonstrate a significant level of ...
Agness Gidna +17 more
core +5 more sources
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
Discursive manoeuvres and hegemonic recuperations in New Zealand documentary representations of domestic violence [PDF]
, 2003 This paper examines three television documentaries--entitled Not Just a Domestic (1994), Not Just a Domestic: The Update (1994), and Picking Up the Pieces (1996)--that together formed part of the New Zealand police ‘Family Violence’ media campaign ...
Michelle, Carolyn, Weaver, C. Kay
core +2 more sources
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
Strategies for building pathology reports in an urban rehabilitation process: Project of the Old City Centre of Coimbra [PDF]
, 2005 The increasing interest on architectural heritage associated to the recognised building value, at economic, social and cultural levels have stimulated, in the recent decades, the urban rehabilitation and renovation o several cities in Europe.
Silva, J. A. R. Mendes da +2 more
core +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source