Results 131 to 140 of about 8,064,509 (338)

Examining Pathological Bias in a Generative Adversarial Network Discriminator: A Case Study on a StyleGAN3 Model [PDF]

open access: yesarXiv
Generative adversarial networks (GANs) generate photorealistic faces that are often indistinguishable by humans from real faces. While biases in machine learning models are often assumed to be due to biases in training data, we find pathological internal color and luminance biases in the discriminator of a pre-trained StyleGAN3-r model that are not ...
arxiv  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Node Similarities under Random Projections: Limits and Pathological Cases [PDF]

open access: yesarXiv
Random Projections have been widely used to generate embeddings for various graph learning tasks due to their computational efficiency. The majority of applications have been justified through the Johnson-Lindenstrauss Lemma. In this paper, we take a step further and investigate how well dot product and cosine similarity are preserved by random ...
arxiv  

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

open access: yesFEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano   +16 more
wiley   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

Semantic distance organizes social knowledge: Insights from semantic dementia and cross-modal conceptual space [PDF]

open access: yesarXiv
Our interaction with others largely hinges on how we semantically organize the social world. The organization of such conceptual information is not static -- as we age, our experiences and ever-changing anatomy alter how we represent and arrange semantic information. How does semantic distance between concepts affect this organization, particularly for
arxiv  

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