Results 111 to 120 of about 4,052,586 (301)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Co-presence Communities: Using pervasive computing to support weak social networks

open access: yes, 2006
Although the strongest social relationships feature most prominently in our lives, we also maintain a multitude of much weaker connections: the distant colleagues that we share a coffee with in the afternoon; the waitress at a our regular sandwich bar ...
De Roure, David   +2 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Replacing the Nods and Smiles: Raising Questions about Philosophy and Pedagogy in a Predominantly Web-based Master’s Module

open access: yesJournal of Open, Flexible and Distance Learning, 2012
This paper discusses the student and lecturer experience of a Master of Education module taught through the World Wide Web and with study guides. It explores the wide range of responses to questions about students' perceptions of the philosophy that ...
Mavis Haigh, Margaret Turnbull
doaj   +2 more sources

Labor market integration in the presence of social capital [PDF]

open access: yes
Labor market integration is typically assumed to improve welfare in the absence of distortions, because it allows labor to move to where returns are highest.
Schiff, Maurice
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Social media presence

open access: yes
Social media presence: Live discussions on Twitter about the project, its results and events. The tweets will be collected and stored as a live story on Storify, which will be constantly updated throughout the project’s life span.
  +10 more sources

Social Injustice From the Presence of the Bauxite Mining Companies [PDF]

open access: yes, 2016
This study aims to examine the forms of social injustice by the presence of mining companies and local residents in the Tayan Hilir, Sanggau. This study used a qualitative approach accomplished through a descriptive method, and which was then analyzed ...
Fatmawati, F. (Fatmawati)   +1 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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