Results 121 to 130 of about 15,880,482 (247)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2013 With the increasing prevalence of online shopping, many companies have added “personalized recommendation” modules on their websites to collect customers’ click-stream data in real time and conduct relevant analysis, which will both ...
Wang, Yong, Li, Yanan
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Materials design in CALL: social presence in online environments
, 2012 Over a decade ago Johnson (1999) pointed out that the potential of technology to transform language teaching was the main assumption underlying CALL course and material design and that conceptual frameworks which emphasize the social, cultural, and ...
Warnecke, Sylvia, Hauck, Mirjam
core +2 more sources
A digital Catholic imagination: Towards Full Presence in dialogue with contemporary social media
Church, Communication and CultureTowards Full Presence represents the first official Church document that addresses the use of social media in its entirety. In this paper, I provide a reflection on three themes emerging in the document in relation to my empirical, sociolinguistic ...
Andre Joseph Theng
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
, 2019 REAL PRESENCE was 10 years, 13 cities, 68 exhibitions in institutions and public locations, 1564 young artists and students from, 105 academies and universities from 37 countries, 150 statements of artists who took part and who are today active and ...
Parsberg, Cecilia,
core
The Nexus between Social Presence, Customer Experience and Purchase Intention in Social Commerce Platform Toward Sustainable Digital Economic Development [PDF]
Social media has transformed the digital landscape from connecting people to connecting supply and demand. Many individuals as well as enterprises engage their customers using social media platforms. Transaction through social media could bring influence
Rachmani Allya, Hanna +1 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source