Results 121 to 130 of about 4,052,586 (301)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Discover EducationAlthough the Community of Inquiry is a widely used instructional model for online and blended learning, there is a lack of comprehensive research on its effects on learner motivation.
Mohamed Shameem Adam +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Challenges and Benefits of Collaborative Work in Online Courses
Online LearningThis investigation examined student experiences with online collaborative learning, focusing on the types and frequency of support received and their relationship to the Community of Inquiry framework.
Sheri Conklin +3 more
doaj +1 more source
Aggregate Savings in the Presence of Private and Social Insurance [PDF]
In the presence of uncertain lifetimes, social security has the characteristics of an annuity: a consumer pays a tax when young in exchange for receiving a social security benefit if he survives to be old.
Andrew B. Abel
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
A digital Catholic imagination: Towards Full Presence in dialogue with contemporary social media
Church, Communication and CultureTowards Full Presence represents the first official Church document that addresses the use of social media in its entirety. In this paper, I provide a reflection on three themes emerging in the document in relation to my empirical, sociolinguistic ...
Andre Joseph Theng
doaj +1 more source
Analyzing covert social network foundation behind terrorism disaster
, 2007 This paper addresses a method to analyze the covert social network foundation hidden behind the terrorism disaster. It is to solve a node discovery problem, which means to discover a node, which functions relevantly in a social network, but escaped from ...
Maeno, Yoshiharu, Ohsawa, Yukio
core +1 more source