Results 101 to 110 of about 2,062,933 (307)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
BMC Primary CareBackground There is growing evidence for the role of culture in supporting health and wellbeing, including as part of social prescribing provision. This study set out to explore the existing cultural provision and mechanisms for connecting people to ...
Anna Dadswell, Hilary Bungay
doaj +1 more source
Derechos sociales y la libertad de establecimiento y prestación de servicios
Revista Vasca de Administración Pública, 2010 The rules about freedom of establishment and services provision have the purpose to remove barriers to carry out an important number of economic activities.
José Ignacio Cubero Marcos
doaj +1 more source
Changing care services and labour markets [PDF]
, 2007 Changes in the nature of funding, in the care sector, are influencing the development of a social care labour market.
Lethbridge, Jane
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Policy and Practice Brief: Expedited Reinstatement of Social Security or SSI Disability Benefits [PDF]
, 2006 This brief covers the expedited reinstatement (EXR) provision, introduced into the Social Security Disability Insurance (SSDI) and Supplemental Security Income (SSI) programs in January 2001.
Sheldon, James R.
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Diversity, Social Goods Provision, and Performance in the Firm [PDF]
The last decade has seen a growing interest among economists on the effect of diversity on the provision of social goods and the stock of social capital.
Jeffrey Greenbaum +2 more
core
For Love and Money: Governance and Social Enterprise [PDF]
, 2007 For Love and Money – Governance and Social Enterprise is the result of research commissioned by the Governance Hub, in partnership with the Social Enterprise Coalition, and conducted by third sector specialists from the Open University. It aims to:
Aiken, Mike +2 more
core