Results 141 to 150 of about 103,199 (263)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Civil society perspectives on tuberculosis care for people living with HIV in Brazil: A study informed by Social Representations Theory. [PDF]

open access: yesPLOS Glob Public Health
Magnabosco GT   +10 more
europepmc   +1 more source

SOCIAL REPRESENTATION OF SEXUAL VIOLENCE

open access: yes, 2012
The present study explored the social representations of sexual violence in Sicilian secondary schools students. Regarding the social representation of sexual violence and its possible causes, it appears to be important the limited meaning given to sexual violence referred only to those behaviors that require physical strength, whereas sexual abuse ...
Castiglione C.   +3 more
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Socioenvironmental conflicts and social representations surrounding mining extractivism at Santurban. [PDF]

open access: yesSci Rep, 2022
Zárate-Rueda R   +2 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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