Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Civil society perspectives on tuberculosis care for people living with HIV in Brazil: A study informed by Social Representations Theory. [PDF]
Magnabosco GT +10 more
europepmc +1 more source
Social representations of malaria in a southern malian community: an ethnographic qualitative study. [PDF]
Sissoko B +3 more
europepmc +1 more source
SOCIAL REPRESENTATION OF SEXUAL VIOLENCE
The present study explored the social representations of sexual violence in Sicilian secondary schools students. Regarding the social representation of sexual violence and its possible causes, it appears to be important the limited meaning given to sexual violence referred only to those behaviors that require physical strength, whereas sexual abuse ...
Castiglione C. +3 more
openaire +2 more sources
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Influence of Religious Commitment on Social Cognition: An Exploratory Study of Social Representations of Peace Among a Sample of Graduates Cameroonians. [PDF]
Etoundi JC, Goujon B, Gaymard S.
europepmc +1 more source
Socioenvironmental conflicts and social representations surrounding mining extractivism at Santurban. [PDF]
Zárate-Rueda R +2 more
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Emotional Content of Social Representations and Interpersonal Communication. [PDF]
Moliner P, Piermattéo A.
europepmc +1 more source
A gender study of the social representations of dating violence in Chilean adolescents. [PDF]
Sanhueza T, Lalande C, Lessard G.
europepmc +1 more source

