Results 151 to 160 of about 2,380,709 (266)

Word embedding for social sciences: an interdisciplinary survey. [PDF]

PeerJ Comput Sci
Matsui A, Ferrara E.
europepmc   +1 more source

Editorial: Methodological issues in psychology and social sciences research. [PDF]

Front Psychol, 2022
Espejo B, Martín-Carbonell M, Checa I.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Perspectives of health, and human and social sciences professionals on student transformation regarding racial discrimination in healthcare. [PDF]

BMC Med Educ
Lambert M, Mansouri M, Mouhab A, Radjack R, Moro MR.   +4 more
europepmc   +1 more source

Approach to theoretical perspectives of "sexual harassment": review and bibliometric analysis from social sciences. [PDF]

Front Psychol, 2023
Cuenca-Piqueras C, Fernández-Prados JS, González-Moreno MJ.   +2 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Evaluation as a translational resource: Bridging social sciences with clinical and translational sciences to advance university, health system, and community initiatives. [PDF]

J Clin Transl Sci
Sperling J, Muhigaba PB, Quenstedt S, Wyman Roth N, Brown A, McClernon FJ.   +5 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Constructing Schwartz values framework using the Rokeach values survey: Human value measurement in the longitudinal internet survey for social sciences. [PDF]

PLoS One
Smallenbroek O, Leijen I, Stanciu A, van Herk H, Bardi A.   +4 more
europepmc   +1 more source