Results 111 to 120 of about 10,367,407 (327)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Providing Long-Term Participation Incentive in Participatory Sensing

, 2016
Providing an adequate long-term participation incentive is important for a participatory sensing system to maintain enough number of active users (sensors), so as to collect a sufficient number of data samples and support a desired level of service ...
Gao, Lin, Hou, Fen, Huang, Jianwei
core   +1 more source

HeteroEdge: taming the heterogeneity of edge computing system in social sensing

International Conference on Internet-of-Things Design and Implementation, 2019
Social sensing has emerged as a new sensing application paradigm where measurements about the physical world are collected from humans or devices on their behalf.
D. Zhang, Md. Tahmid Rashid, Xukun Li, Nathan Vance, Dong Wang   +4 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Flood Inundation Probability Estimation by Integrating Physical and Social Sensing Data: Case Study of 2021 Heavy Rainfall in Henan, China

Remote Sensing
Frequent flooding seriously affects people’s safety and economic construction, and assessing the inundation probability can help to strengthen the capacity of emergency management of floods.
Wenying Du, Qingyun Xia, Bingqing Cheng, Lei Xu, Zeqiang Chen, Xiang Zhang, Min Huang, Nengcheng Chen   +7 more
doaj   +1 more source

Sensor Networks: Physical and Social Sensing in the IoT. [PDF]

Sensors (Basel), 2023
De S, Moessner K.
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Dynamic Assessment of Population Exposure to Urban Flooding Considering Building Characteristics

Land
Under intensifying climate change impacts, accurate quantification of population exposure to urban flooding has become an imperative component of risk mitigation strategies, particularly when considering the dynamic nature of human mobility patterns ...
Shaonan Zhu, Xin Yang, Jiabao Yang, Jun Zhang, Qiang Dai, Zhenzhen Liu   +5 more
doaj   +1 more source

Persuasive design of a mobile energy conservation game with direct feedback and social cues [PDF]

, 2009
Pervasive gaming has the potential of transforming the home into a persuasive environment in which the user can learn about appliances and their electricity consumption.
Bång, Magnus, Gustafsson, Anton, Svahn, Mattias   +2 more
core   +1 more source