Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The Impact of Social Work Students’ Experience with Supervision
Journal of Social Work Education and PracticeThe study intends to describe and explore the quality of the implementation of supervision training at the Faculty of Social Studies, University of Ostrava.
Karla Pobucká +3 more
doaj +4 more sources
Challenges for Peacebuilding and Citizenship Learning in Colombia
Magis: Revista Internacional de Investigación en Educación, 2019 Some education practices can impede learning democratic citizenship agency by reinforcing injustices or omitting dissenting perspectives. Other practices may help address conflict issues through problem-posing inquiry activities. This literature review
Ángela María Guerra-Sua
doaj +1 more source
Using Curriculum Mapping as a Tool to Match Student Learning Outcomes and Social Studies Curricula. [PDF]
Front Psychol, 2022 Okojie MU, Bastas M, Miralay F.
europepmc +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Exploring Possibilities of an Undergirding Umunthu Philosophy in Malawi’s Social Studies Curriculum
Ethiopian Journal of the Social Sciences and Humanities, 2019 The article explores possibilities of integrating Umunthu values into the social studies in Malawi with the purpose of reforming the curriculum into one that is relatable and relevant to the local needs of the society.
Beaton Galafa
doaj +1 more source
Sociodemographics and Transdiagnostic Mental Health Symptoms in SOCIAL (Studies of Online Cohorts for Internalizing Symptoms and Language) I and II: Cross-sectional Survey and Botometer Analysis. [PDF]
JMIR Form Res, 2022 Lorenzo-Luaces L +6 more
europepmc +1 more source