Results 101 to 110 of about 5,017,199 (310)

The Effect of Digital Learning Media Utilization and Learning Motivation on Learning Participation

open access: yesJurnal Inovasi Pendidikan dan Sains
This study aims to analyze the effects of digital learning media and learning motivation on students’ learning participation in the Science and Social Science (IPAS) subject at the elementary school level.
Siti Asrofah   +2 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Dark personality traits and deception, and the short dark tetrad (SD4) as integrity screening instrument

open access: yesScientific Reports
Dark personality traits (Machiavellianism, Narcissism, Psychopathy, and Sadism) have been associated with aversive, unethical, and criminal conduct. Concise measurement tools such as the Short Dark Tetrad (SD4) are popular, because they lend themselves ...
Eric Rassin   +2 more
doaj   +1 more source

Service Difficulties, Internal Resolution Mechanisms, and the Needs of Social Services in Hungary—The Baseline of a Development Problem Map

open access: yesSocial Sciences
This study focuses on the current service/care difficulties and challenges that social institutions in Hungary are facing during their daily operations; how they can react to them utilizing their internal resources, mechanisms, and capacities; and what ...
Zoltán Csizmadia   +3 more
doaj   +1 more source

Pedagogy - a holistic, personal approach to work with children and young people, across services: European models for practice, training, education and qualification [PDF]

open access: yes, 2009
Today, provision for children and young people is developing rapidly at the level of policy, organisation, training, education, and qualifications. Research in these areas, carried out at the Thomas Coram Research Unit (TCRU), has included cross-national
Boddy, Janet   +6 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

A New Framework for Assessing the Benefits of Early Education [PDF]

open access: yes, 2004
This working paper is among a series of papers funded by the Pew Charitable Trusts through its "Advancing Quality Pre-K for All" initiative. The paper proposes that future preschool valuations devote appropriate attention to the related potential long ...

core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

TRICHOTILLOMANIA: EDUCATIONAL ISSUES [PDF]

open access: yes, 2009
Twenty journal articles that examined the condition trichotillomania that are included in national journal databases created for educators were reviewed by a special education teacher. The articles were classified by publication type (e.g., empirical
Voth, David
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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