Results 111 to 120 of about 28,097,799 (251)

The Effect of Digital Learning Media Utilization and Learning Motivation on Learning Participation

open access: yesJurnal Inovasi Pendidikan dan Sains
This study aims to analyze the effects of digital learning media and learning motivation on students’ learning participation in the Science and Social Science (IPAS) subject at the elementary school level.
Siti Asrofah   +2 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Preservice Teachers’ Ecological Citizenship Model: A Grounded Theory Research

open access: yesAustralian Journal of Environmental Education
This study explores how preservice social studies teachers conceive ecological citizenship and evaluates a curriculum-embedded ecological citizenship model intended to cultivate environmentally responsible citizens.
Caner Dalli, Ercenk Hamarat
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Barriers and facilitators during the implementation process of shared decision-making in the comorbidity field: staff perspectives

open access: yesNordic Social Work Research
To enhance user participation in the complex setting of coordinating support, more knowledge is needed about strategies designed to improve user involvement.
Amanda Jones   +2 more
doaj   +1 more source

Exclusion and neoliberalism in the education system: socio-educational intervention strategies for an inclusive education system [PDF]

open access: yes, 2018
Not only numerous academic and empirical studies recognise the educational factor as decisive on life and work trajectories, but also its integrating potential and role in the promotion of social cohesion are widely acknowledged. The diversity of current
Rodríguez Fernández, Juan Ramón   +1 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Moderating learner-centred pedagogy in the relationship between study habits and deep learning in accounting education

open access: yesDiscover Education
This study investigates the relationship between study habits and deep learning in accounting education, with particular attention to the moderating role of learner-centred pedagogy.
Maclean Bajimpong Betakan   +1 more
doaj   +1 more source

Service Difficulties, Internal Resolution Mechanisms, and the Needs of Social Services in Hungary—The Baseline of a Development Problem Map

open access: yesSocial Sciences
This study focuses on the current service/care difficulties and challenges that social institutions in Hungary are facing during their daily operations; how they can react to them utilizing their internal resources, mechanisms, and capacities; and what ...
Zoltán Csizmadia   +3 more
doaj   +1 more source

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