Results 101 to 110 of about 1,287,849 (314)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

SSE500

open access: yes, 2017
Classroom and field experiences designed to help students make better-informed decisions regarding careers in secondary social studies education. The definition and purpose of social studies; current research trends in social studies education.
Social Studies Education
core  

Environmental perceptions and social support as predictors of continued participation in nighttime physical activity

open access: yesBMC Public Health
Objective Guided by the Theory of Planned Behavior (TPB), this study investigates how perceived environment and social support are associated with the intention to sustain nighttime physical activity, with attitude tested as a mediating variable. Methods
Minghui Zhao   +4 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Adolescent Mental Health from the Perspective of Ki Hadjar Dewantara

open access: yesJurnal Ilmiah Bimbingan Konseling Undiksha
The background of this research was based on the rising prevalence of mental disorders among adolescents, triggered by academic pressure, social dynamics, family environment, and the influence of the digital world.
Arya Djodipati, Poerwanti Hadi Pratiwi
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Marital control, domestic violence justification, and mental health: a study of married women in Bangladesh

open access: yesBMC Psychiatry
Marital control and culturally accepted justifications of domestic violence are pervasive forms of gendered power imbalances that undermine women’s autonomy and significantly contribute to adverse mental health outcomes.
Mortuja Mahamud Tohan   +5 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Rebuilding the past through dusty stuff: How Turkish students respond to primary source based social studies education?

open access: yes, 2020
While the use of primary sources in education has long been an object of interest, their adoption is still lacking in social studies courses in Turkey. This work presents the results of a qualitative study conducted with the participation of 37 students ...
Akbulut, Melisa, Açikalin, Mehmet
core  

INTEGRATING LOCAL COFFEE POTENTIAL INTO SOCIAL STUDIES USING COMMUNITY-BASED LEARNING TO ENHANCE STUDENTS’ CREATIVITY

open access: yesJurnal Pendidikan Ilmu Sosial
This study explores the integration of local coffee potential into Social Studies learning through a Community-Based Learning (CBL) approach to enhance students’ creativity in junior high schools located in coffee-producing areas of Jember Regency ...
Amri Dhimas Maulana   +5 more
doaj  

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