Results 131 to 140 of about 5,594,537 (351)

Distinguishing Topical and Social Groups Based on Common Identity and Bond Theory

open access: yes, 2013
Social groups play a crucial role in social media platforms because they form the basis for user participation and engagement. Groups are created explicitly by members of the community, but also form organically as members interact.
Aiello, Luca Maria   +3 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

The depoliticization of protest: understanding the 2024/2025 Serbian students’ uprising

open access: yesCogent Social Sciences
The 2024/2025 student protests in Serbia emerged in the wake of a deadly infrastructural collapse in Novi Sad, catalyzing nationwide outrage and revealing systemic failures rooted in corruption and political cronyism.
Aleksandra Jerkov   +2 more
doaj   +1 more source

Small task-oriented groups : a systems analysis : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Education at Massey University [PDF]

open access: yes, 1972
Where two or more people are gathered together in order to engage in social interaction - there is a social system". (Anon.) The question of why it is that people come together in systems of interaction and how these systems persist as viable social ...
Harvey, Judith Ceridwen Irangani   +1 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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