FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Predictors of Readmission to an Acute Psychiatric Inpatient Unit
BJPsych OpenAims The Acute Mental Health Inpatient Centre is an 80 bed acute psychiatric inpatient unit in Belfast. The inpatient unit is frequently over capacity resulting in the use of contingency beds or delays in accessing acute inpatient care.
Aidan Turkington, Emily Stirling
doaj +1 more source
Impact of value similarity on social trust in medical students: a cross-sectional web survey. [PDF]
BMC Med Educ, 2023 Kondo S, Ichikawa S, Izumiya M, Eto M.
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Extending the Reach of the STOMP Initiative to a Residential Nursing Home in Northern Ireland
BJPsych OpenAims STOMP (stopping the over-medication of people with a learning disability, autism, or both) is a national project launched by NHS England in 2016. The objective is to curb the excessive use of psychotropic medication in individuals with a learning ...
Emily Stirling, Michael Doris
doaj +1 more source
Using portraits to quantify the changes of generalized social trust in European history: A replication study. [PDF]
PLoS One, 2023 Guillou L, Safra L, Baumard N.
europepmc +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Loneliness, Social Support, Social Trust, and Subjective Wellness in Low-Income Children: A Longitudinal Approach. [PDF]
Children (Basel), 2023 Akgül H, Güven AZ, Güven S, Ceylan M.
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The Role of Subjective Wellbeing in Mediating Social Trust to the Mental Health of Health Workers. [PDF]
Healthcare (Basel), 2023 Xiong C +5 more
europepmc +1 more source