Results 91 to 100 of about 2,045,222 (347)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Designing a Valid & Reliable Tool for Assessing the Occupational Therapist\'s Clinical Competency

Journal of Rehabilitation, 2014
Objective: The aim of study was to design a valid and reliable tool for assessing the occupational therapists’ clinical competency. Materials & Methods: It was a tool-making study.
Azadeh Jabbari, Mohammad Ali Hosseini, Saeed Fatoureh-Chi, Ali Hosseini, Marjan Farzi   +4 more
doaj  

Inequality and Social Welfare [PDF]

This paper provides a review of part of the literature on inequality and social welfare, with a special focus on the Gini index. The paper first presents the extended Gini index used for measuring inequality, as well as the source decomposition of the ...
Wodon, Quentin, Yitzhaki, Shlomo
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A Comparison of Metaphoric Expressions Comprehension in Mainstreaming Students with Severe Hearing Impairment and Hearing Students of Junior High School

Journal of Rehabilitation, 2010
Objective: Many researchers believe hearing impaired people suffer from special disability in metaphor comprehension. This study was aimed to compare the comprehension of metaphoric expressions in mainstreaming sever hearing impaired and normal students ...
Reyhaneh Mohammadi, Tahereh-Sima Shirazi, Reza Nilipour, Mahdi Rahgozar, Abbas Pourshahbaz   +4 more
doaj  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Domains, Components and Indicators of Children’s Wellbeing in Iran: A Delphi Study

مجله اپیدمیولوژی ایران, 2018
Background and Objectives: Children’s well-being is a multidimensional construct that precedes various aspects of childrenchr('39')s lives. This study sought to identify the main areas of childrenchr('39')s wellbeing in Iran and their domains, components,
H Sajadi, M Vameghi, F Mohammadi Shahboulaghi, D Ali, SH Mohaqeqi Kamal   +4 more
doaj  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Analysis of the Influence of School for Great Women (Sekolah Perempuan Hebat) Model on Family Resilience in Dano Village Indonesia

ASEAN Social Work Journal
The government's efforts to protect and empower women are realized through the School for Great Women model. The problem of the study is how the School for Great Women Model influence family resilience in Dano Indonesia Village.
Bambang Rustanto, Theresia Martina Marwanti, Tuti Kartika Kartika, Dela Vinka Ariska   +3 more
doaj   +1 more source

The concept of social care and the analysis of contemporary welfare states [PDF]

, 2000
Mary E. Daly, Jane Lewis
openalex   +1 more source