Results 81 to 90 of about 1,069,613 (212)
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Strengths-Based Social Work: Proposing Protective and Engagement Practice with Older Adults [PDF]
Journal of Social Work Education and Practice, 2018 This article proposes Strengths-Based Protective (SB-P) and Strengths-Based Engagement (SB-E) social work practice model with older adults with particular reference to living in older care homes.
Vishal M. V.
doaj
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
TRAUMA IS THE “STEALING OF MY SENSE OF BEING ME”: A PERSON-CENTRED PERSPECTIVE ON TRAUMA
Social Work/Maatskaplike Werk, 2012 Exposure to trauma has always been part of human existence (Marsella, Friedman & Spain, 1996). Extreme stress has been depicted by authors throughout the ages.
Barbara Wade, Rinie Schenck
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Private refugee sponsorship in Canada
Forced Migration Review, 2017 For almost four decades, groups of Canadian private citizens have sponsored refugees for resettlement in addition to federal government resettlement programmes.
Jennifer Hyndman +2 more
doaj
POVERTY IN A RURAL AREA: THE ROLE OF THE SOCIAL WORKER
Social Work/Maatskaplike Werk, 2008 There are many ways of looking at poverty. When poverty is measured in absolute terms, itrefers to the financial means necessary for people to survive from day to day.
C Strydom, ME Tlhojane
doaj +1 more source
Golden-rule social security and public health in a dynastic model with endogenous longevity and fertility [PDF]
In this paper we investigate long-run optimal social security and public health and their effects on fertility, longevity, capital intensity, output per worker and welfare in a dynastic model with altruistic bequests.
Jie Zhanga, Siew Ling Yew
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source