Results 71 to 80 of about 2,189,001 (293)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Intercultural relations, bodies speech and semiopraxis [PDF]
Alteridad : Revista de Educación, 2010 La línea de investigación que proponemos pone en diálogo el trabajo conjunto de redes de investigación latinoamericana, fundamentalmente,las que tienen vinculación con movimientos y actores sociales, no necesariamente académicos, como por ejemplo el ...
José Luis Grosso
doaj
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Effects of social disruption in elephants persist decades after culling. [PDF]
, 2013 BACKGROUND Multi-level fission-fusion societies, characteristic of a number of large brained mammal species including some primates, cetaceans and elephants, are among the most complex and cognitively demanding animal social systems. Many free-ranging
Cynthia Moss +7 more
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Revista Latino-Americana de Enfermagem, 2000 Utilizando-se de uma abordagem qualitativa, esse artigo delineia a percepção de profissionais de saúde, sobretudo pediatras, acerca da violência e sua responsabilidade em denunciar os casos que vivenciaram.
Marlene Braz, Maria Helena C.A. Cardoso
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Проблеми на постмодерността, 2012 Communication and globalization are strongly linked processes, and in this article is shown just that, as well as the "noises" which prevent meaningful communication of the societies.
Evgeni Vasilev
doaj
Primates et Sociétés : La sortie de l’état de nature
Revue de Primatologie, 2012 Rousseau’s three centenary is a good opportunity to introduce his fundamental ideas and to apply them to new domains, such as primatology. The concept of the state of nature, developed in the first part of the second Discourse, and the dichotomy between ...
Thomas Robert +1 more
doaj +1 more source