Results 81 to 90 of about 467,478 (277)
Assessing the hepatoprotective efficacy of Vitis gracilis Wall. against doxorubicin-induced hepatic injury in rats [PDF]
Journal of Pharmacy & Pharmacognosy ResearchContext: Doxorubicin is an anticancer drug that can adversely affect the liver. Therefore, seeking medical attention to manage pain and minimize side effects is crucial.
Yurnadi Hanafi Midoen +2 more
doaj +1 more source
Advanced Science, EarlyView.6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi +12 more
wiley +1 more source
Advanced Science, EarlyView.The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen +11 more
wiley +1 more source
Role of antioxidant supplementation and exercise regimen in handling oxidative stress from natural PM2.5 exposure due to boreal forest fire [PDF]
, 2019 Thesis (M.S.) University of Alaska Fairbanks, 2019Particulate matter 2.5 (PM2.5) exposure induces oxidative stress that causes many negative health outcomes such as cancer, cardiovascular disease and neurodegenerative disease. Research shows that dietary
Witkop, Jacob J.
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Engineering MnPt Bimetallic Nanozymes for Cascade Enzymatic Therapy and Enhanced Radio‐Immunotherapy
Advanced Science, EarlyView.A CD44‐targeted MnPt bimetallic nanozyme (HD@MnO2) integrates multienzyme‐like activity with cGAS–STING activation to boost radio‐immunotherapy. Through cascade biocatalysis, it depletes glutathione, relieves hypoxia, and amplifies ROS, enhancing radiotherapy‐induced DNA damage and immunogenic cell death. The nanozyme promotes dendritic cell maturation
Wenyi Zhang +8 more
wiley +1 more source
Bioinspired catalysts: Synthesis, characterisation and some applications [PDF]
, 2008 Our recent work concerning the synthesis, characterisation and some applications of bioinspired electron-transfer catalysts is reviewed in this contribution.
Pálinkó, István
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Advanced Science, EarlyView.Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan +8 more
wiley +1 more source
The effect of cryoprotectant on the quality of post-warming goat oocytes by examining SOD levels
Open Veterinary JournalBackground: Vitrification of oocytes can lead to the formation of reactive oxygen species during the in vitro maturation and warming processes. In this study, there is a comparison between the use of commercial cryoprotectant and ethylene glycol ...
Meisa Zalfa Adisti +7 more
doaj +1 more source
Advanced Science, EarlyView.A “polymer‐in‐cage” strategy transforms a zinc‐acrylate copolymer into an active pore‐modulating agent for ZIF‐8 nanoplates. The polymer actively tunes the MOF's pore structure by anchoring within its windows, while the nanoplates create tortuous pathways.
Minsu Kim +9 more
wiley +1 more source
HaematologicaIntroduction: ITP is an autoimmune disorder characterized by isolated thrombocytopenia caused by immune-mediated platelet destruction and insufficient platelet production, resulting in an increased bleeding risk. Thrombopoietin receptor agonists (TPO-RAs)
A. Baffioni +4 more
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