Results 81 to 90 of about 468,553 (276)

History of pain theories (Storie delle teorie del dolore)

Pathos, 2013
The history of pain is as long as that of the human race. Several theories have been developed but none of them are yet exhaustive. Historically, the clinical approach has reflected the vision that society had about pain.
Mirko Silvestrini, Claudio A. Caputi
doaj  

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

Role of antioxidant supplementation and exercise regimen in handling oxidative stress from natural PM2.5 exposure due to boreal forest fire [PDF]

, 2019
Thesis (M.S.) University of Alaska Fairbanks, 2019Particulate matter 2.5 (PM2.5) exposure induces oxidative stress that causes many negative health outcomes such as cancer, cardiovascular disease and neurodegenerative disease. Research shows that dietary
Witkop, Jacob J.
core  

Regulation of Excitonic Behavior in Defective Acetylenic Polymers Enables Mechanism Switching in O2 Activation for Enhanced Water Decontamination

Advanced Science, EarlyView.
A molecular defect‐mediated charge accumulation strategy is developed to regulate the exciton behavior for selective molecular oxygen (O2)activation in poly(1,3,5‐triethynylbenzene) (PTEB). Artificial internal electric field (IEF) constructed in defective PTEB provides internal driving force to steer the directed migration of charge carriers, thereby ...
Xiaofeng Tang, Sijia Jin, Wei Li, Yingrong Wang, Haiyan Zhang, Zhiqiao He, Shuang Song, Yaqi Cai, Tao Zeng   +8 more
wiley   +1 more source

Bioinspired catalysts: Synthesis, characterisation and some applications [PDF]

, 2008
Our recent work concerning the synthesis, characterisation and some applications of bioinspired electron-transfer catalysts is reviewed in this contribution.
Pálinkó, István
core  

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

The effect of cryoprotectant on the quality of post-warming goat oocytes by examining SOD levels

Open Veterinary Journal
Background: Vitrification of oocytes can lead to the formation of reactive oxygen species during the in vitro maturation and warming processes. In this study, there is a comparison between the use of commercial cryoprotectant and ethylene glycol ...
Meisa Zalfa Adisti, Widjiati Widjiati, Agus Sunarso, Epy Muhammad Luqman, Tri Wahyu Suprayogi, Sri Pantja Madyawati, Suzanita Utama, Aulia Firmawati   +7 more
doaj   +1 more source

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

Advanced Science, EarlyView.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men, Chenchen Wu, Lei Wang, Shengjie Gao, Yu Mao, Wei Liu, Changhong Liu, Lei Zheng   +7 more
wiley   +1 more source

P131 | EVALUATION OF PLATELET RESPONSE IN CHRONIC ITP PATIENTS TREATED WITH A PERSONALIZED DOSING REGIMEN OF AVATROMBOPAG: A SINGLE-CENTER COHORT ANALYSIS

Haematologica
Introduction: ITP is an autoimmune disorder characterized by isolated thrombocytopenia caused by immune-mediated platelet destruction and insufficient platelet production, resulting in an increased bleeding risk. Thrombopoietin receptor agonists (TPO-RAs)
A. Baffioni, C. Giubbilei, G. Giustini, A.M. Vannucchi, V. Carrai   +4 more
doaj  

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source