Catalytic Antioxidant Activity of Bis-Aniline-Derived Diselenides as GPx Mimics [PDF]
Molecules, 2021 Herein, we describe a simple and efficient route to access aniline-derived diselenides and evaluate their antioxidant/GPx-mimetic properties. The diselenides were obtained in good yields via ipso-substitution/reduction from the readily available 2 ...
Giancarlo V Botteselle +2 more
exaly +5 more sources
Research progress of glutathione peroxidase family (GPX) in redoxidation
Frontiers in Pharmacology, 2023 Maintaining the balance of a cell’s redox function is key to determining cell fate. In the critical redox system of mammalian cells, glutathione peroxidase (GPX) is the most prominent family of proteins with a multifaceted function that affects almost all cellular processes.
Jun Pei
exaly +4 more sources
Translational regulation of GPx-1 and GPx-4 by the mTOR pathway.
PLoS ONE, 2014 Glutathione peroxidase activity was previously determined to be elevated in lymphocytes obtained from patients treated with the Bcr-Abl kinase inhibitor imatinib mesylate.
Emily N Reinke +4 more
doaj +3 more sources
Going Forward and Back: The Complex Evolutionary History of the GPx
Biology, 2021 There is large diversity among glutathione peroxidase (GPx) enzymes regarding their function, structure, presence of the highly reactive selenocysteine (SeCys) residue, substrate usage, and reducing agent preference.
Thomaz Stumpf Trenz +2 more
exaly +3 more sources
Clitorea ternatea flower extract induces platelet-derived growth factor (PDGF) and GPx gene overexpression in ultraviolet (UV) B irradiationinduced collagen loss [PDF]
Medicinski Glasnik, 2023 Aim To determine the effect of Clitorea ternatea flower extract (CTFE) in the gel dosage form on the expression of GPx and platelet-derived growth factor (PDGF) in ultraviolet (UV) - B irradiation-induced collagen loss rat model.
Rizka Sofyanti Putri +7 more
doaj +1 more source
Antioxidant Activity of Tempeh Ethanolic Extract on Male Swiss Mouse Brain
Majalah Obat Tradisional, 2023 Tempeh is an Indonesian food made of soybean (Glycine max (L.) Merr.) by fermentation using Rhizopus spp mold. Soybean has a high content of protein, fatty acids, vitamins, and isoflavone glycosides. Isoflavone glycosides are poorly absorbed in the human
Yohanes Dwiatmaka +3 more
doaj +1 more source
Valproic Acid Attenuates Oxidative Damage in Rat Spleen Tissue Induced By Spinal Cord Damage
Turkish Journal of Agriculture: Food Science and Technology, 2022 Events such as oxidative stress caused by spinal cord injury (SCI) are a serious condition because they negatively affect many organs. Alternative treatment options for this type of injury are quite limited.
Mustafa Ulaş
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Trakya University Journal of Natural Sciences, 2022 An ischemia/reperfusion (IR) injury of small intestine is a serious and common condition that is a result of the blockage of the superior mesenteric artery (SMA) due to some significant clinical problems.
Ayşegül Çerkezkayabekir +4 more
doaj +1 more source
Expression of antioxidant enzymes genes in the liver and cardiac tissues of rats under L-carnitine administration and high-intensity interval exercise training [PDF]
The Ukrainian Biochemical Journal, 2021 Reactive oxygen and nitrogen species are produced in the body both in normal and pathological processes and can alter cell redox and affect cell functions. Exercise training is able to modulate oxidant/antioxidants balance.
B. Shahouzehi +3 more
doaj +1 more source
CONCURRENT EFFECT OF LINUM USITATISSIMUM AND EMBLICA OFFICINALIS ON LEAD INDUCED OXIDATIVE STRESS AND HISTOMORPHOLOGICAL CHANGES IN UTERUS OF FEMALE WISTAR RATS [PDF]
Exploratory Animal and Medical Research, 2022 Lead (Pb) is one of the oldest environmental contaminants and is well known to cause deleterious systemic effects on man and domestic animals including the reproductive system.
Amitava Paul, Karamala Sujatha
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