Results 1 to 10 of about 61,907 (295)
Going Forward and Back: The Complex Evolutionary History of the GPx [PDF]
Biology, 2021 There is large diversity among glutathione peroxidase (GPx) enzymes regarding their function, structure, presence of the highly reactive selenocysteine (SeCys) residue, substrate usage, and reducing agent preference.
Thomaz Stumpf Trenz +2 more
exaly +7 more sources
Translational regulation of GPx-1 and GPx-4 by the mTOR pathway.
PLoS ONE, 2014 Glutathione peroxidase activity was previously determined to be elevated in lymphocytes obtained from patients treated with the Bcr-Abl kinase inhibitor imatinib mesylate.
Emily N Reinke +4 more
doaj +4 more sources
ВЕТЕРИНАРСКИ ЖУРНАЛ РЕПУБЛИКЕ СРПСКЕ, 2022 Glutathione peroxidase (GPx) is an enzyme that has 8 isoenzyme forms, of which GPx-1 is an obligatory intracellular enzyme, while GPx-3 is active in extracellular fluids, especially in blood plasma. The main role of GPx is the protection of cells from oxidative stress induced by free oxygen radicals.
Valčić, Olivera +3 more
openaire +3 more sources
MiR-146b-5p regulates the scavenging effect of GPx-3 on peroxide in papillary thyroid cancer cells
Heliyon, 2023 Background: Glutathione peroxidase (GPx) is an important antioxidant enzyme in thyroid follicular cells. Reduced levels of glutathione peroxidase 3 (GPx-3) expression in papillary thyroid cancer (PTC) are associated with poor prognosis.
Dan Zhang, Jun Jiang
exaly +3 more sources
Catalytic Antioxidant Activity of Bis-Aniline-Derived Diselenides as GPx Mimics
Molecules, 2021 Herein, we describe a simple and efficient route to access aniline-derived diselenides and evaluate their antioxidant/GPx-mimetic properties. The diselenides were obtained in good yields via ipso-substitution/reduction from the readily available 2 ...
Giancarlo V Botteselle +2 more
exaly +3 more sources
Clitorea ternatea flower extract induces platelet-derived growth factor (PDGF) and GPx gene overexpression in ultraviolet (UV) B irradiationinduced collagen loss [PDF]
Medicinski Glasnik, 2023 Aim To determine the effect of Clitorea ternatea flower extract (CTFE) in the gel dosage form on the expression of GPx and platelet-derived growth factor (PDGF) in ultraviolet (UV) - B irradiation-induced collagen loss rat model.
Rizka Sofyanti Putri +7 more
doaj +1 more source
Antioxidant Activity of Tempeh Ethanolic Extract on Male Swiss Mouse Brain
Majalah Obat Tradisional, 2023 Tempeh is an Indonesian food made of soybean (Glycine max (L.) Merr.) by fermentation using Rhizopus spp mold. Soybean has a high content of protein, fatty acids, vitamins, and isoflavone glycosides. Isoflavone glycosides are poorly absorbed in the human
Yohanes Dwiatmaka +3 more
doaj +1 more source
Valproic Acid Attenuates Oxidative Damage in Rat Spleen Tissue Induced By Spinal Cord Damage
Turkish Journal of Agriculture: Food Science and Technology, 2022 Events such as oxidative stress caused by spinal cord injury (SCI) are a serious condition because they negatively affect many organs. Alternative treatment options for this type of injury are quite limited.
Mustafa Ulaş
doaj +1 more source
Trakya University Journal of Natural Sciences, 2022 An ischemia/reperfusion (IR) injury of small intestine is a serious and common condition that is a result of the blockage of the superior mesenteric artery (SMA) due to some significant clinical problems.
Ayşegül Çerkezkayabekir +4 more
doaj +1 more source
Reports of Biochemistry and Molecular Biology, 2023 This study aimed to investigate the GPx-1 gene polymorphism (rs1050450), the level of oxidative stress and antioxidant parameters, and the lipid profile in an obese Kurdish population in Sulaimani, Iraq.In a case-control study,134 obese subjects and 131 normal BMI healthy individuals participated.
Avan Arif, Ahmad +4 more
openaire +2 more sources