Results 41 to 50 of about 48,780 (260)

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

Advanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang, Jiaxin Tian, Xiaolong Zhu, Xiao Li, Xiangshu Qiu, Yuanyuan Li, Ben Zhong Tang, Ning Shi   +7 more
wiley   +1 more source

Glutathione Peroxidase in Stable Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis

Antioxidants, 2021
Chronic obstructive pulmonary disease (COPD) is a progressive disease that is characterized by a state of persistent inflammation and oxidative stress.
Elisabetta Zinellu, Angelo Zinellu, Maria Carmina Pau, Barbara Piras, Alessandro G. Fois, Sabrina Mellino, Ciriaco Carru, Arduino A. Mangoni, Pietro Pirina   +8 more
doaj   +1 more source

АКТИВНОСТ СЕЛЕНОЕНЗИМА GPx-1 И GPx-3 У КРВИ РАДНИХ КОЊА НА ТЕРИТОРИЈИ ЦЕНТРАЛНЕ СРБИЈЕ

ВЕТЕРИНАРСКИ ЖУРНАЛ РЕПУБЛИКЕ СРПСКЕ, 2022
Глутатион пероксидаза (GPx) је ензим који постоји у 8 изоензимских облика, од којих GPx-1 је облигаторни интрацелуларни ензим, док је GPx-3 активна у екстрацелуларним течностима, посебно у крвној плазми. Основна улога GPx се огледа у заштити ћелија од оксидативног стреса којег индукују слободни кисеонични радикали.
openaire   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Response of Anti-Oxidative Stress Genes in Liver and Intestine in Broilers Fed Organic Acid and Silver Nanoparticles Coated on Zeolite in Starter Period [PDF]

پژوهشهای تولیدات دامی
Extended Abstract Background: The use of food supplements to improve growth, optimal production and increase feed efficiency in feeding livestock and poultry has become a common thing as a suitable solution in using feed as well as possible.
Fatemeh Asgharnezhad, Seyed Reza Hashemi, Saeed Hassani, Sharif Rostami   +3 more
doaj  

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

Advanced Science, EarlyView.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou, Caixi Yu, Guilan Xu, Lijuan Liu, Yujia Liang, Yulin Liang, He Ding, Litu Zhang, Piaoping Yang, Chen Wang   +9 more
wiley   +1 more source

SEMINAL PLASMA GLUTATHIONE PEROXIDASE IN RELATION TO FUNCTIONAL COMPETENCE OF CRYOPRFSERVED BUFFALO SPERMATOZOA [PDF]

Veterinary Medical Journal - Giza, 2005
Glutathione peroxidase (GPx) has a central role in the defense against oxidative damage: however, data on GPx activity in the buffalo semen is limited. To expand this knowledge GPx activity in the seminal plasma of buffalo-bulls was studied.
M Waheed, Mona Alaa Alaa El-Deen, K El-Shahat, T Khalifa, A Ghalab   +4 more
doaj   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source

Glutathione peroxidase-1 primes pro-inflammatory cytokine production after LPS challenge in vivo. [PDF]

PLoS ONE, 2012
Reactive oxygen species produced during the innate immune response to LPS are important agents of anti-pathogen defence but may also cause oxidative lung damage.
Steven Bozinovski, Huei Jiunn Seow, Peter J Crack, Gary P Anderson, Ross Vlahos   +4 more
doaj   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source