Results 61 to 70 of about 92,722 (279)

Aktivnost selenoenzima GPx-1 i GPx-3 u krvi radnih konja na teritoriji centralne Srbije

, 2022
Глутатион пероксидаза (GPx) је ензим који постоји у 8 изоензимских облика, од којих GPx-1 је облигаторни интрацелуларни ензим, док је GPx-3 активна у екстрацелуларним течностима, посебно у крвној плазми. Основна улога GPx се огледа у заштити ћелија од оксидативног стреса којег индукују слободни кисеонични радикали.
Valčić, Olivera, Milosavljević, Petar, Jovanović, Ivan B., Milanović, Svetlana   +3 more
openaire   +1 more source

Bifunctional Artificial Enzymes‐Loaded Microgels With LOX‐ and CAT‐Like Activities for Metabolic Reprogramming and Scarless Wound Repair

Advanced Science, EarlyView.
A bifunctional lactate oxidase‐like and catalase‐like artificial enzyme (Metazyme) is integrated into a rod‐shaped microgel (MetaRgel) to enable cascade lactate oxidation and oxygen regeneration. By reprogramming the wound metabolic microenvironment, MetaRgel alleviates excessive lactate accumulation, oxidative stress, hypoxia, and inflammation ...
Yongyuan Kang, Pai Peng, Liang Song, Qiaoxuan Wang, Zilong Zhong, Dongchao Qiu, Yunfan Liu, Kefei Zhao, Xiaofei Dong, Changyou Gao   +9 more
wiley   +1 more source

Glutathione peroxidase-1 primes pro-inflammatory cytokine production after LPS challenge in vivo. [PDF]

PLoS ONE, 2012
Reactive oxygen species produced during the innate immune response to LPS are important agents of anti-pathogen defence but may also cause oxidative lung damage.
Steven Bozinovski, Huei Jiunn Seow, Peter J Crack, Gary P Anderson, Ross Vlahos   +4 more
doaj   +1 more source

Association of GPX1 polymorphism, GPX activity and prostate cancer risk

Human & Experimental Toxicology, 2011
Prostate cancer is the second most common cancer in men worldwide. Although the aetiology of this disease remains largely unclear, several lines of evidence suggest that oxidative stress plays a role in prostate carcinogenesis. The antioxidant enzyme glutathione peroxidase 1 (GPX1) is part of the enzymatic antioxidant defence, preventing oxidative ...
Erdem, Onur, Eken, Ayse, Akay, Cemal, Arsova-Sarafinovska, Zorica, Matevska, Nadica, Suturkova, Ljubica, Erten, Koray, Ozgok, Yasar, Dimovski, Aleksandar, Sayal, Ahmet, Aydin, Ahmet   +10 more
openaire   +5 more sources

Liver‐Targeted Gallium‐Polyphenol Network by Disrupting the ROS/NETs/PANoptosis Axis for Precision Acute Liver Injury Therapy

Advanced Science, EarlyView.
ABSTRACT Acute liver injury (ALI), driven by diverse insults such as drug toxicity and ischemia‐reperfusion, poses a high mortality risk and lacks targeted therapies. While reactive oxygen species (ROS), neutrophil extracellular traps (NETs), and a coordinated cell death pathway PANoptosis have been implicated, their interplay as a unified pathogenic ...
Xiaopeng Cai, Jian He, Jingwen Deng, Ziwei Wang, Zhongshu Wu, Kaiyue Wang, Xiang Zheng, Zhenzhen Gao, Xi Ma, Shumei Wei, Xiangrong Hu, Yuan Ding, Weilin Wang, Min Zhou   +13 more
wiley   +1 more source

Response of Anti-Oxidative Stress Genes in Liver and Intestine in Broilers Fed Organic Acid and Silver Nanoparticles Coated on Zeolite in Starter Period [PDF]

پژوهشهای تولیدات دامی
Extended Abstract Background: The use of food supplements to improve growth, optimal production and increase feed efficiency in feeding livestock and poultry has become a common thing as a suitable solution in using feed as well as possible.
Fatemeh Asgharnezhad, Seyed Reza Hashemi, Saeed Hassani, Sharif Rostami   +3 more
doaj  

Exploiting Query Structure and Document Structure to Improve Document Retrieval Effectiveness [PDF]

, 2006
In this paper we present a systematic analysis of document retrieval using unstructured and structured queries within the score region algebra (SRA) structured retrieval framework.
Apers, P.M.G., Blok, H.E., Hiemstra, D., Mihajlovic, V.   +3 more
core   +2 more sources

Influence of hyperhomocysteinemia on the cellular redox state - Impact on homocysteine-induced endothelial dysfunction [PDF]

, 2003
Hyperhomocysteinemia is an independent risk factor for the development of atherosclerosis. An increasing body of evidence has implicated oxidative stress as being contributory to homocysteines deleterious effects on the vasculature.
Adachi T, Andersson A, Bagi Z, Bellamy MF, Chambers JC, Chambers JC, Chao CL, Flohé L, Forgione MA, Guttormsen AB, Huang R-FS, Kanani PM, Karlsson K, Lang D, Lentz SR, Mansoor MA, Mansoor MA, Mansoor MA, Mansoor MA, O'Donnell VB, Outinen PA, Pritchard, Rubbo H, Tawakol A, Ungvari Z, Weiss N, Wilcken DE, Woo KS, Zhang F, Zhang X   +29 more
core   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

Effects of selenide chitosan sulfate on glutathione system in hepatocytes and specific pathogen-free chickens

Poultry Science, 2020
This study aimed to investigate the effects of selenide chitosan sulfate (Se-CTS-S) on glutathione (GSH) system in hepatocytes and chickens. Chitosan, sodium selenite (Na2SeO3), selenide chitosan, chitosan sulfate (CTS-S), and Se-CTS-S were added to the ...
Fu Chen, Lele Hou, Lianqin Zhu, ChengboYang, Fenghua Zhu, Huiling Qiu, Shunyi Qin   +6 more
doaj   +1 more source