Results 251 to 260 of about 72,561 (329)

Transcriptional modulation unique to vulnerable motor neurons predicts ALS across species and SOD1 mutations. [PDF]

Genome Res
Mei I, Nichterwitz S, Leboeuf M, Nijssen J, Lenoel I, Repsilber D, Lobsiger CS, Hedlund E.   +7 more
europepmc   +1 more source

3P059 Elimination of post-translational modifications in SOD1 leads to form pathological amyloid-like aggregates in familial ALS(Proteins-stability, folding, and other physicochemical properties,Oral Presentations)

, 2007
Yoshiaki Furukawa, Kumi Kaneko, Koji Yamanaka, Nobuyuki Nukina   +3 more
openalex   +2 more sources

Characterization of a Bioprinted Anticancer Cell Therapy System Generated with Continuous Liquid Interface Production

Advanced NanoBiomed Research, Volume 5, Issue 10, October 2025.
Cell therapies often fail in the clinic due to poor in vivo persistence. In this study, we developed a 3D bioprinting strategy using continuous liquid interface production (CLIP) to generate cell therapy delivery systems. We provide a robust characterization of this new technique, demonstrating the positive effect of CLIP bioprinting on the efficacy of
Lauren Kass, Ike Keku, Yu Zhang, Justin Forbes, Morrent Thang, Jillian Perry, Shawn Hingtgen   +6 more
wiley   +1 more source

High-order single-nucleotide polymorphism interactions between selected anti-oxidant and protease genes influence North Indians' propensity for chronic obstructive pulmonary disease (COPD) and lung function parameters. [PDF]

Hum Genomics
Kansal H, Chopra V, Garg K, Sharma S.
europepmc   +1 more source

Faculty Opinions recommendation of Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis.

, 2007
Stanley H. Appel
openalex   +2 more sources

The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence

Brain and Behavior, Volume 15, Issue 10, October 2025.
This study delineates the multiple pathways leading to stroke, encompassing genetic risk factors such as lipid/cholesterol metabolism, blood pressure regulation genes, and endothelial dysfunction. The report includes genetic pathways such as Val66Met polymorphism, prothrombin G20210A, interleukin‐6 and tumor necrosis factor gene variant, along with ...
Mega Obukohwo Oyovwi, Benneth Ben‐Azu, Ejayeta Jeroh, Faith B. Friday   +3 more
wiley   +1 more source

Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice

, 2008
Rebecca Banerjee, R. Lee Mosley, Ashley Reynolds, Alok Dhar, Vernice Jackson‐Lewis, Gordon Gilbert, Serge Przedborski, Howard E. Gendelman   +7 more
openalex   +2 more sources

Cancer and Post‐Therapy Cardiotoxicity Risk in Adolescents, Young Adults, and Adults With Down Syndrome

Comprehensive Physiology, Volume 15, Issue 5, October 2025.
Adults with down syndrome are more likely to develop hematological malignancies and testicular cancer. Additionally, they are more susceptible to cardiovascular diseases after anthracycline treatment. Created with BioRender.com. ABSTRACT The median life expectancy of people with Down syndrome has increased substantially over the past several decades ...
Michelle A. Buckman, Anastasiia Vasileva, Charles R. Jedlicka, Hardik Kalra, Mikhail Vasilyev, David S. Dickens, Michael H. Tomasson, Melissa L. Bates   +7 more
wiley   +1 more source

Entering the era of precision medicine to treat amyotrophic lateral sclerosis. [PDF]

Mol Neurodegener
Theunissen F, Flynn L, Iacoangeli A, Al Khleifat A, Al-Chalabi A, Giordano JJ, Strømme M, Akkari PA.   +7 more
europepmc   +1 more source

Individual and Comorbid Influences of Chronic Stress and a Western Diet on Allostatic Loads and Cardiac Resilience, Adaptation and Proteome Profiles in Male Mice

Comprehensive Physiology, Volume 15, Issue 5, October 2025.
These findings support positive interactions between common risk factors in comorbid development of cardiovascular and affective disorders. Mitochondrial and innate defense paths may contribute to the influences of diet, stress, and preconditioning.
Makayla Nicholas, Tessa Helman, Brock Lyon, Saba Naghipour, Trissha Ybanez, Joshua T. Ingles, Chulkyu Kim, Nicolas J. C. Stapelberg, Jason N. Peart, John P. Headrick, Eugene F. du Toit   +10 more
wiley   +1 more source