Results 61 to 70 of about 2,627 (289)

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang   +8 more
wiley   +1 more source

EFFECTS OF SILICON AND CALCIUM APPLICATION ON GROWTH, YIELD AND FRUIT QUALITY PARAMETERS OF CUCUMBER ESTABLISHED IN A SODIC SOIL

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2020
Soil salinity is a growing problem that affects crop quality. Cucumber is a vegetable eaten fresh, with great worldwide demand, making its chemical and physical characteristics important. In the present work, the effects of foliar application of silicon (
Gustavo E. González-Terán   +2 more
doaj   +1 more source

Quantitative Dissection of Sodicity Tolerance in Wheat

open access: yes, 2020
Sodicity tolerance limits for varietal selection and sustaining wheat productivity in salt affected ...

core  

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

open access: yesAdvanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka   +4 more
wiley   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

open access: yesAdvanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou   +8 more
wiley   +1 more source

Chitosan and Brassinosteroids Mitigate Ion Imbalance and Enhancing Stolon Production in Strawberry

open access: yesInternational Journal of Plant Biology
Excess sodium in soil disrupts ionic balance and limits water uptake, negatively affecting growth and stolon production in strawberry plants. This study assessed the effects of chitosan (CTS), brassinosteroids (BRs), and thidiazuron (TDZ) on stolon ...
Miriam Elizabeth Martínez-Pérez   +6 more
doaj   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi   +12 more
wiley   +1 more source

Farmers' ability to cope with salinity and sodicity: Farmers' perceptions, strategies and practices for dealing with salinity and sodicity in their farming systems [PDF]

open access: yes
Soil salinity / Sodic soils / Farming systems / Farmers' attitudes / Soil properties / Soil classification / Soil management / Irrigation water / Water quality / Pakistan / Punjab / Chishtian Sub-Division / Fordwah ...
Kielen, N. C.
core  

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan   +10 more
wiley   +1 more source

Sodicity classes for soil surface and coverage area of salinity zones in the study area.

open access: yes, 2021
Sodicity classes for soil surface and coverage area of salinity zones in the study area.
Elif Günal (11285749)
core   +1 more source

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