Results 111 to 120 of about 4,121,484 (357)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Comparison of Urinary Sodium and Blood Pressure Relationship From the Spot Versus 24‐Hour Urine Samples

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background We compared the relationship between sodium (Na) intake and blood pressure when Na intake was estimated from first‐ and second‐morning spot urine samples using the INTERSALT (International Study on Salt and Blood Pressure) formula, versus ...
Abu Mohd Naser, Mahbubur Rahman, Leanne Unicomb, Solaiman Doza, Shuchi Anand, Howard H. Chang, Stephen P. Luby, Thomas F. Clasen, K.M. Venkat Narayan   +8 more
doaj   +1 more source

Transparent dense sodium

, 2009
Under pressure, metals exhibit increasingly shorter interatomic distances. Intuitively, this response is expected to be accompanied by an increase in the widths of the valence and conduction bands and hence a more pronounced free-electron-like behaviour.
Andriy O. Lyakhov, AR Oganov, AR Oganov, Artem R. Oganov, CW Glass, E Gregoryanz, E Gregoryanz, G Kresse, G Kresse, I Tamblyn, Ivan Trojan, JB Neaton, JB Neaton, JL Dye, JM Leger, JP Perdew, JY Raty, K Shimizu, M Hanfland, M Hanfland, M Shishkin, Mario Valle, MI Eremets, MI McMahon, Mikhail Eremets, NE Christensen, PE Blöchl, S Deemyad, Sergey Medvedev, Vitali Prakapenka, VV Struzhkin, X Gonze, Y Ma, Y Ma, Yanming Ma, Yu Xie   +35 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Screening 215 Lentil Genotypes under Salinity Stress During the Seedling Stage in Greenhouse Conditions [PDF]

پژوهشنامه اصلاح گیاهان زراعی
Extended abstract Background: Salinity stress is one of the environmental stresses that significantly affects the growth of crops, especially in arid and semi-arid regions.
Ahmad Nezami, jafar Nabati, Mohammad Kafi, Elahe Boroumand Rezazadeh   +3 more
doaj  

Effectiveness of a Self-monitoring Device for Urinary Sodium-to-Potassium Ratio on Dietary Improvement in Free-Living Adults: a Randomized Controlled Trial

Journal of Epidemiology, 2018
Background: Reducing the urinary sodium-to-potassium ratio is important for reducing both blood pressure and risk of cardiovascular disease. Among free-living Japanese individuals, we carried out a randomized trial to clarify the effect of lifestyle ...
Toshiyuki Iwahori, Hirotsugu Ueshima, Naoto Ohgami, Hideyuki Yamashita, Naoko Miyagawa, Keiko Kondo, Sayuki Torii, Katsushi Yoshita, Toshikazu Shiga, Takayoshi Ohkubo, Hisatomi Arima, Katsuyuki Miura   +11 more
doaj   +1 more source

Synergistic Approach for Disinfestation of Heat-Resistant Fungal Conidia in Grain Spawn Production: Combining Cold Plasma and Sodium Hypochlorite Treatments [PDF]

, 2023
Saba Bakhtiarvandi, Hamid Reza Samadlouie, Seyed Iman Hosseini, Shideh Mojerlou, Patrick J. Cullen   +4 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Sodium and chloride data from selected streams in the Lassen area, north-central California, and their relation to thermal-fluid discharge from the Lassen hydrothermal system [PDF]

, 1991
K.M. Paulson, S. E. Ingebritsen
openalex   +1 more source

Improved chlorate candle provides concentrated oxygen source [PDF]

, 1967
Improved chlorate candle is used as a solid, portable source of oxygen in emergency situations. It contains sodium chlorate, iron, barium peroxide, and glass mixed in powdered form. The oxygen evolves from the decomposition of the sodium chlorate when an
Haug, R. D., Myers, D. A., Tanzar, G. F.
core   +1 more source