Results 91 to 100 of about 2,714,980 (262)
Current Developments in NutritionBackground: High sodium intake is a major risk factor for noncommunicable diseases, with most Canadians exceeding recommended levels. Population-wide sodium-reduction interventions include monitoring sodium knowledge, attitudes, and behaviors as a core ...
Rola Al Ghali +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
IUCrData, 2016 In the title compound, [Na2(C16H7Cl3N5O2)2(CH3OH)4]·C4H10O·2CH3OH, the central pyrazolo[3,4-d]pyrimidine system makes dihedral angles of 82.98 (7)° with the trichlorophenyl ring and 13.11 (15)° with the pyridine ring.
Bassam Abu Thaher +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background We compared the relationship between sodium (Na) intake and blood pressure when Na intake was estimated from first‐ and second‐morning spot urine samples using the INTERSALT (International Study on Salt and Blood Pressure) formula, versus ...
Abu Mohd Naser +8 more
doaj +1 more source
Sodium-Ion Storage Mechanism in Triquinoxalinylene and a Strategy for Improving Electrode Stability
, 2020 Sodium-ion batteries are a promising alternative to lithium-ion batteries. In particular, organic sodium-ion batteries employing environmentally friendly organic materials as electrodes are gaining increasing research interest for developing secondary ...
Cheng Zhang (70708) +6 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Journal of Epidemiology, 2018 Background: Reducing the urinary sodium-to-potassium ratio is important for reducing both blood pressure and risk of cardiovascular disease. Among free-living Japanese individuals, we carried out a randomized trial to clarify the effect of lifestyle ...
Toshiyuki Iwahori +11 more
doaj +1 more source
Overcoming sodium toxicity by utilizing grass leaves as co-substrate during the start-up of batch thermophilic anaerobic digestion [PDF]
, 2012 Sodium toxicity is a common problem causing inhibition of anaerobic digestion, and digesters treating highly concentrated wastes, such as food and municipal solid waste, and concentrated animal manure, are likely to suffer from partial or complete ...
Suwannoppadol, S. +2 more
core